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A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.
Topical cosmetic. Cysteamine 5% cream is typically applied once daily to areas of melasma as a short-contact treatment (left on for ~15 minutes, then washed off) to limit odor and irritation, with daily sunscreen. There is no oral or systemic use in this context. This library does not provide an ingestion protocol.
Any time
Cysteamine 5% cream (short-contact application)
Topical cosmetic only. Niacinamide is typically formulated at 2-5% in leave-on serums, creams, or gels and applied to clean skin once or twice daily (AM and/or PM). It layers well under sunscreen and with most other actives. There is no oral, injectable, or systemic dose in this cosmetic context — it is not ingested here. This library does not provide an ingestion protocol.
Any time
Leave-on topical serum or cream (2-5% niacinamide)
Throughout
8-16 weeks
Throughout
Throughout
4-12 weeks
2-12 weeks
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