Compare Supplements

Approved BPH dose is 0.5 mg once daily; off-label hair-loss use mirrors the same 0.5 mg once-daily dose under a clinician. A prescription drug.

Morning

Oral soft-gel capsule (dutasteride 0.5 mg)

Prescription-only and indication-dependent. For fertility preservation / intratesticular-testosterone maintenance on TRT, small studies used ~125-500 IU subcutaneously every other day. For spermatogenesis induction in hypogonadotropic hypogonadism, typically ~1,000-2,500 IU two to three times weekly (often combined with FSH), titrated to response. For female ovulation/oocyte-maturation trigger, a single dose (~5,000-10,000 IU urinary or 250 µg recombinant). No dietary-supplement dose exists.

Any time

Prescription hCG — recombinant (choriogonadotropin alfa) or urinary-derived, by injection

• Women who are or may become pregnant (risk to a male fetus — DHT is required for male genital development)
• Children
• Known hypersensitivity to dutasteride or other 5α-reductase inhibitors

• Strong CYP3A4 inhibitors (e.g. ritonavir, ketoconazole)
• Tamsulosin / alpha-blockers

• Hormone-sensitive tumors (e.g. prostate, breast) or other androgen/estrogen-dependent conditions
• Known hypersensitivity to hCG
• Use without medical supervision

• Exogenous testosterone / anabolic steroids
• FSH / hMG (menotropins)
• Aromatase inhibitors (e.g. anastrozole)