Compare Supplements

Approved BPH dose is 0.5 mg once daily; off-label hair-loss use mirrors the same 0.5 mg once-daily dose under a clinician. A prescription drug.

Morning

Oral soft-gel capsule (dutasteride 0.5 mg)

Topical 2–5% solution or 5% foam applied to the scalp (men: 5% twice daily or once-daily foam; women: 2% twice daily or 5% foam once daily). Low-dose ORAL minoxidil is off-label and clinician-titrated, typically 0.25–5 mg once daily. A drug — not an approved supplement regimen.

Morning

Topical 5% foam/solution (OTC) for most; low-dose oral minoxidil under a clinician for poor topical responders

• Women who are or may become pregnant (risk to a male fetus — DHT is required for male genital development)
• Children
• Known hypersensitivity to dutasteride or other 5α-reductase inhibitors

• Strong CYP3A4 inhibitors (e.g. ritonavir, ketoconazole)
• Tamsulosin / alpha-blockers

• Pheochromocytoma (oral — vasodilator)
• Significant uncontrolled cardiovascular disease without clinician oversight (oral)
• Known hypersensitivity to minoxidil or vehicle (e.g., propylene glycol in some topicals)

• Other antihypertensives / vasodilators
• Guanethidine