Compare Supplements

Side-by-side comparison of 2 supplements

Dut5.4

Dutasteride

Limited safety

Py5.5

Pygeum

High safety

Evidence

Mostly mechanism / observational

Evidence Score5.4/10

Studies: 7

Meta-analyses: 3

Likely helps

Evidence Score5.5/10

Studies: 23

Meta-analyses: 1

Dosage & timing

Dosage:

Approved BPH dose is 0.5 mg once daily; off-label hair-loss use mirrors the same 0.5 mg once-daily dose under a clinician. A prescription drug.

Best Time:

Morning

Can take on empty stomach

Form:

Oral soft-gel capsule (dutasteride 0.5 mg)

Dosage:

150mg

Best Time:

Any time · with food (preferred)

Can take on empty stomach

Form:

Standardized extract (13-14% sterols)

What you'll notice

💇 Hair regrowth / retentionpositive

3–6 months

🚹 Prostate shrinkage & BPH symptom reliefpositive

Months

🔬 Lower overall prostate-cancer detectiontrade-off

Years

💧 Improved Urinary Flowpositive

6-8 weeks

🌙 Reduced Nighttime Urinationpositive

6-8 weeks

👍 Prostate Comfortpositive

8-12 weeks

Safety

Limited safety

Contraindications:

Women who are or may become pregnant (risk to a male fetus — DHT is required for male genital development)
Children
Known hypersensitivity to dutasteride or other 5α-reductase inhibitors

Drug Interactions:

Strong CYP3A4 inhibitors (e.g. ritonavir, ketoconazole)
Tamsulosin / alpha-blockers

Side Effects:

Decreased libidoErectile / ejaculatory dysfunctionDepressed mood

High safety

Contraindications:

Hormone-sensitive conditions (theoretical)

Drug Interactions:

5-alpha reductase inhibitors (finasteride, dutasteride)
Alpha-blockers (tamsulosin)

Side Effects:

GI upsetNausea

Works well with

No synergies listed

Saw Palmetto

complementary

Stinging Nettle Root

complementary

Pumpkin Seed Oil

complementary

How they work together

Like what you see? Add these to your stack.

See how they work together through biological pathways.

Build Your Stack

Want to compare more supplements?

Loading comparison...