Compare Supplements

Standard approved dosing is 140 mg subcutaneously every 2 weeks OR 420 mg subcutaneously once monthly, under a clinician. A prescription drug; this is informational, not a recommendation.

Any time

Subcutaneous prefilled autoinjector (evolocumab)

10 mg once daily, with or without food, alone or added to a statin — under a clinician. A prescription drug; not a self-directed supplement regimen.

Any time

Oral tablet (ezetimibe 10 mg)

• Prior serious hypersensitivity reaction to evolocumab
• Use only under clinician direction as part of a lipid-management plan

• Statins
• Ezetimibe

• Active liver disease or unexplained persistent transaminase elevations (when combined with a statin)
• Pregnancy and breastfeeding (especially in combination with a statin)
• Known hypersensitivity to ezetimibe

• Bile-acid sequestrants (cholestyramine, colesevelam)
• Statins
• Cyclosporine