Compare Supplements

Side-by-side comparison of 2 supplements

Gly6.5

Glycine

High safety

Mel8.5

Melatonin

High safety

Evidence

Likely helps

Evidence Score6.5/10

Studies: 27

Meta-analyses: 4

Likely helps

Evidence Score8.5/10

Studies: 1204

Meta-analyses: 23

Dosage & timing

Dosage:

Best Time:

Before bed

Can take on empty stomach

Form:

Powder (dissolves easily, tastes sweet)

Dosage:

1mg

Best Time:

Before bed

Can take on empty stomach

Form:

Immediate-release tablet or sublingual

What you'll notice

😴 Better Subjective Sleep Qualitypositive

First few nights

⚡ Less Next-Day Fatiguepositive

Next morning

🍬 Sweet Tasteneutral

Immediate

⏱️ Faster Sleep Onsetpositive

Same night

✈️ Jet Lag Reliefpositive

1-3 days

😵 Morning Grogginesstrade-off

Next morning

Safety

High safety

Contraindications:

Clozapine users (glycine may affect drug efficacy)

Drug Interactions:

Clozapine
Other sleep aids

Side Effects:

GI discomfortVivid dreams

High safety

Contraindications:

Autoimmune disorders (may stimulate immune activity)
Seizure disorders (consult doctor)

Drug Interactions:

Blood thinners
Immunosuppressants
Sedatives/CNS depressants (incl. benzodiazepines, alcohol)

Side Effects:

Morning drowsinessHeadacheVivid dreams/nightmares

Works well with

stacks-well

complementary

stacks-well

complementary

stacks-well

complementary

How they work together

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