Compare Supplements

Side-by-side comparison of 2 supplements

Hch7.0

Horse Chestnut

Moderate safety

Vc8.0

Vitamin C

High safety

Evidence

Evidence Score7/10

Studies: 11

Meta-analyses: 2

Evidence Score8/10

Studies: 43

Meta-analyses: 16

Outcome Grades

Reduce inflammationC

Reduce inflammationB

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Dosage & timing

Dosage:

300mg standardized extract twice daily (providing ~50mg aescin per dose; ~100mg aescin/day)

Best Time:

With meals · with food

Take with food

Form:

Aescin-standardized, enteric-coated seed extract

Dosage:

1500mg

Best Time:

Split through the day · with food (preferred)

Take with food

Form:

Ascorbic acid or buffered vitamin C

What you'll notice

🦵 Reduced leg swellingpositive

2-12 weeks

💢 Reduced leg pain/heavinesspositive

2-8 weeks

⚠️ Occasional GI upsettrade-off

Days

🛡️ Immune Supportpositive

Ongoing

⚡ Reduced Oxidative Stresspositive

1-2 weeks

✨ Skin Healthpositive

4-8 weeks

Safety

Moderate safety

Contraindications:

Kidney or liver disease
Bleeding disorders or anticoagulant use
Pregnancy and breastfeeding

Drug Interactions:

Anticoagulants/antiplatelets
Nephrotoxic drugs
Antidiabetic medications

Side Effects:

GI upsetDizziness/headacheItching

High safety

Contraindications:

History of kidney stones (use caution with high doses)
Hemochromatosis (iron overload disorder)

Drug Interactions:

Blood thinners (Warfarin)
Chemotherapy drugs

Side Effects:

DiarrheaNauseaKidney stones

Works well with

complementary

complementary

complementary

complementary

enhances

complementary

How they work together

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