Compare Supplements

Side-by-side comparison of 2 supplements

Lgg6.0

L. rhamnosus GG

High safety

LF6.3

Lactoferrin

Moderate safety

Evidence

Mostly mechanism / observational

Evidence Score6/10

Studies: 44

Meta-analyses: 8

Mostly mechanism / observational

Evidence Score6.3/10

Studies: 30

Meta-analyses: 8

Dosage & timing

Dosage:

10-20 billion CFU (1-2 x 10^10) daily; 10 billion CFU/day is the effective floor

Best Time:

Any time · with food

Take with food

Form:

Capsule standardized to ATCC 53103

Dosage:

300mg

Best Time:

Between meals

Can take on empty stomach

Form:

Bovine lactoferrin capsule or powder (≥95% purity)

What you'll notice

💊 Fewer antibiotic-associated diarrhea episodespositive

During the antibiotic course

🏥 Less hospital-acquired diarrhea in childrenpositive

During hospital stay

🚫 No benefit for treating a stomach bugnegative

n/a

🛡️ Fewer Respiratory Infectionspositive

4–8 weeks of use

🩸 Improved Iron Statuspositive

4–8 weeks

🔥 Lower Inflammatory Markerspositive

4–8 weeks

Safety

High safety

Contraindications:

Immunocompromise or immunosuppression (transplant, chemotherapy, advanced HIV)
Critical illness / ICU admission
Indwelling central venous catheter

Drug Interactions:

Systemic antibiotics
Immunosuppressants

Side Effects:

Mild gas or bloatingBloodstream infection (bacteremia)

Moderate safety

Contraindications:

Known allergy to bovine milk proteins (risk of cross-reactivity)
Hemochromatosis or iron overload conditions (holo-lactoferrin form could worsen iron loading)
Active malignancy — theoretical concern due to growth-promoting activity on epithelial cells (consult oncologist)

Drug Interactions: