Compare Supplements

Off-label longevity/muscle-aging use mirrors low antihypertensive dosing (25–100 mg once daily) under a clinician. Not an approved longevity or anti-sarcopenia regimen; blood pressure, kidney function, and potassium should be monitored.

Any time

Oral tablet (losartan potassium)

500mg

Morning · with food (preferred)

Nicotinamide Riboside Chloride capsules or powder

• Pregnancy (fetal harm)
• Bilateral renal artery stenosis
• Hyperkalemia

• Potassium-sparing diuretics / potassium / salt substitutes
• NSAIDs
• Lithium

• Known hypersensitivity to nicotinamide riboside or niacin derivatives
• Active cancer or cancer history: NAD+ elevation may theoretically support tumor cell metabolism (consult oncologist before use)
• Severe hepatic impairment: high-dose NAD+ precursors may affect liver metabolism

• Chemotherapy agents
• PARP inhibitors (e.g., olaparib, niraparib)
• Alcohol