Compare Supplements

Off-label longevity/muscle-aging use mirrors low antihypertensive dosing (25–100 mg once daily) under a clinician. Not an approved longevity or anti-sarcopenia regimen; blood pressure, kidney function, and potassium should be monitored.

Any time

Oral tablet (losartan potassium)

5–20 mg once daily (up to 40 mg in selected high-risk patients), titrated to LDL/ApoB targets — under a clinician. A prescription drug; not a self-directed supplement regimen.

Any time

Oral tablet (rosuvastatin 5–20 mg)

• Pregnancy (fetal harm)
• Bilateral renal artery stenosis
• Hyperkalemia

• Potassium-sparing diuretics / potassium / salt substitutes
• NSAIDs
• Lithium

• Active liver disease or unexplained persistent transaminase elevations
• Pregnancy and breastfeeding
• Known hypersensitivity to rosuvastatin

• Cyclosporine
• Gemfibrozil
• Certain antivirals / protease inhibitors