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A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.
Topical cosmetic only. Leave-on mandelic acid is used at roughly 5-10% in serums; professional peels use higher strengths (often a salicylic-mandelic combination). Apply to clean skin, building frequency as tolerated, with daily sunscreen. There is no oral or systemic dose — it is not ingested. This library does not provide an ingestion protocol.
Evening
Leave-on serum (≈5-10% mandelic acid) or a professional (salicylic-)mandelic peel
Topical OTC use. Leave-on and wash-off acne products contain 0.5-2% salicylic acid, applied to affected areas once or twice daily and built up as tolerated; professional peels (20-30%) are applied in-office. There is no oral or systemic dose in this context — it is not ingested (and large-area/high-concentration use can cause systemic salicylate absorption, so follow label limits). This library does not provide an ingestion protocol.
Any time
Leave-on or wash-off acne product (0.5-2% salicylic acid)
Throughout
8-12 weeks
8-12 weeks
Throughout
4-12 weeks
4-12 weeks
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