Compare Supplements

Topical cosmetic only. Leave-on mandelic acid is used at roughly 5-10% in serums; professional peels use higher strengths (often a salicylic-mandelic combination). Apply to clean skin, building frequency as tolerated, with daily sunscreen. There is no oral or systemic dose — it is not ingested. This library does not provide an ingestion protocol.

Evening

Leave-on serum (≈5-10% mandelic acid) or a professional (salicylic-)mandelic peel

Prescription topical: a pea-sized amount of 0.025%-0.1% cream or gel applied to clean, dry skin once nightly. Start low-strength and every-other-night to build tolerance. A prescription drug used under clinician direction — not a supplement regimen.

Before bed

Topical cream or gel, 0.025%-0.1% (prescription)

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to AHAs
• Active dermatitis or broken/sunburned skin until healed

• Other leave-on actives (retinoids, other acids)

• Pregnancy and planning pregnancy (topical retinoid — avoid)
• Breastfeeding (avoid application near areas of infant contact)
• Eczema / rosacea-prone or broken/sunburned skin (irritation)

• Benzoyl peroxide
• Other topical exfoliants (AHAs / BHAs, abrasives)
• Photosensitizing drugs