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Topical cosmetic only. Matrixyl (palmitoyl pentapeptide-4 / pal-KTTKS, or the Matrixyl 3000 blend of palmitoyl tripeptide-1 + palmitoyl tetrapeptide-7) is used at very low concentrations in leave-on serums and creams — clinical benefit was shown at as little as 3 ppm pal-KTTKS, and consumer products commonly list 3-10% of the branded blend. Applied to the target area once or twice daily. There is no oral, injectable, or systemic dose — it is not ingested.

Any time

Leave-on topical cosmetic (serum or cream) containing palmitoyl pentapeptide-4 or the Matrixyl 3000 blend

Topical OTC. Apply a broad-spectrum SPF 30+ sunscreen daily to sun-exposed skin as the last step of a morning routine, using an adequate amount (about 2 mg/cm² — roughly a nickel-sized dollop for the face, a shot-glass for the body) and reapply every ~2 hours of sun exposure and after swimming/sweating. Mineral (zinc oxide / titanium dioxide) filters are preferred if you're concerned about systemic absorption. There is no oral or systemic dose — it is not ingested. This library does not provide an ingestion protocol.

Morning

Broad-spectrum SPF 30+, applied daily; mineral (zinc oxide/titanium dioxide) if concerned about absorption

• For topical (skin) use only — not for ingestion, not for injection
• Known allergy or sensitivity to the peptide or formulation excipients
• Application to broken, irritated, or compromised skin until healed

• Other topical actives (retinoids, acids)

• For topical (skin) use only — not for ingestion
• Known allergy/sensitivity to a specific UV filter (switch to a mineral filter)

• Other leave-on actives