Compare Supplements

Side-by-side comparison of 2 supplements

Om39.0

Omega-3

High safety

SGE6.0

Sage

Limited safety

Evidence

Evidence Score9/10

Studies: 87

Meta-analyses: 25

Evidence Score6/10

Studies: 22

Meta-analyses: 2

Outcome Grades

NeuroprotectionA

Reduce inflammationA

Support moodA

Menopause supportB

Sharpen focusB

Improve memory & learningB

Reduce anxiety & stressB

NeuroprotectionC

Reduce inflammationC

Support moodC

Menopause supportC

Sharpen focusC

Improve memory & learningC

Reduce anxiety & stressC

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Pooled effect-size head-to-headBeta

Direct side-by-side from the meta-analysis. Each row is an outcome where ≥2 of your selected supplements have pooled data. Best effect per row highlighted.

Outcome	Omega-3	Sage
Support mood — Depression − better · points (PHQ-9)	−3.4best weak	−1.4 weak · CI ∋ 0

Click an outcome to see the full ranked table on the goal page.

Dosage & timing

Dosage:

2g EPA+DHA

Best Time:

With meals · with food

Take with food

Form:

Triglyceride form fish oil

Dosage:

300mg standardized extract

Best Time:

With meals · with food

Take with food

Form:

Standardized extract (300–600 mg, 2.5% rosmarinic acid)

What you'll notice

😊 Improved Moodpositive

4-8 weeks

💪 Reduced Inflammationpositive

2-4 weeks

🐟 Fishy Aftertastetrade-off

Immediate

🧠 Improved Memory & Recallpositive

4–8 weeks

🌡️ Reduced Hot Flashespositive

4–8 weeks

😊 Mood Enhancementpositive

4–8 weeks

Safety

High safety

Contraindications:

Fish/shellfish allergy (use algae-based)
Upcoming surgery (stop 1-2 weeks before)

Drug Interactions:

Blood thinners (warfarin, aspirin)
Blood pressure medications

Side Effects:

Fishy burps/aftertasteGI upsetEasy bruising

Limited safety

Contraindications:

Epilepsy or seizure disorders (thujone content may lower seizure threshold)
Pregnancy (may stimulate uterine contractions; avoid therapeutic doses)
Hormone-sensitive cancers (estrogenic activity; consult oncologist)

Drug Interactions:

Anticoagulants (warfarin, heparin)
Antidiabetic drugs (metformin, insulin, sulfonylureas)
Anticonvulsants (phenytoin, valproate, carbamazepine)

Side Effects:

Nausea or GI upsetDry mouthDizziness or headache

Works well with

complementary

enhances

complementary

complementary

complementary

stacks-well

How they work together

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Outcome

Omega-3

Sage

Support mood — Depression

− better · points (PHQ-9)

−3.4best

weak

−1.4

weak · CI ∋ 0