Compare Supplements

5–20 mg once daily (up to 40 mg in selected high-risk patients), titrated to LDL/ApoB targets — under a clinician. A prescription drug; not a self-directed supplement regimen.

Any time

Oral tablet (rosuvastatin 5–20 mg)

Approved antihypertensive dosing is 20–80 mg once daily; the metabolic/PPARγ effects are most evident at the higher 80 mg (and study) doses, under a clinician. Not an approved metabolic or longevity regimen; blood pressure, kidney function, and potassium should be monitored.

Morning

Oral tablet (telmisartan)

• Active liver disease or unexplained persistent transaminase elevations
• Pregnancy and breastfeeding
• Known hypersensitivity to rosuvastatin

• Cyclosporine
• Gemfibrozil
• Certain antivirals / protease inhibitors

• Pregnancy (fetal harm)
• Bilateral renal artery stenosis
• Hyperkalemia

• ACE inhibitors (dual RAS blockade)
• Potassium-sparing diuretics / potassium / salt substitutes
• NSAIDs