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St. John's Wort

9/10caution

Evidence

Evidence Score9/10

Studies: 40+

Meta-analyses: 17

Dosage & Timing

Dosage:

300mg 3x daily (900mg total)

Best Time:

With meals, Divided into 2-3 doses

Take with food

Form:

Standardized extract (0.3% hypericin)

What You'll Notice

😊 Improved Mood70%

4-6 weeks

😴 Better Sleep55%

4-8 weeks

☀️ Sun Sensitivity20%

During use

Safety

caution safety rating

Contraindications:

Currently taking prescription antidepressants
Bipolar disorder (may trigger mania)
Before surgery (2 weeks prior)

Drug Interactions:

SSRIs/SNRIs/MAOIs
Birth control pills
Blood thinners (Warfarin)

Side Effects:

PhotosensitivityGI discomfortHeadache

Works Well With

Saffronstacks-well

Compare Supplements

St. John's Wort

Evidence

Dosage & Timing

What You'll Notice

Safety

Works Well With

Categories

Compare Supplements

St. John's Wort

Evidence

Dosage & Timing

What You'll Notice

Safety

Works Well With

Categories