Compare Supplements

Side-by-side comparison of 2 supplements

Vd7.5

Vitamin D3

High safety

Vk6.0

Vitamin K2

Moderate safety

Evidence

Evidence Score7.5/10

Studies: 93

Meta-analyses: 21

Evidence Score6/10

Studies: 55

Meta-analyses: 9

Outcome Grades

Bone healthB

Menopause supportB

Prenatal supportB

Healthy agingC

Reduce inflammationC

Build strength & muscleC

Bone healthB

Menopause supportC

Prenatal supportC

Healthy agingB

Reduce inflammationC

Build strength & muscleD

A-F grade per outcome, combining overall evidence with goal-specific relevance. A = strong evidence; F = insufficient. Hover a badge for details.

Pooled effect-size head-to-headBeta

Direct side-by-side from the meta-analysis. Each row is an outcome where ≥2 of your selected supplements have pooled data. Best effect per row highlighted.

Outcome	Vitamin D3	Vitamin K2
Bone health — Bone Mineral Density + better · % BMD change	+0.5 weak	+0.9best weak

Click an outcome to see the full ranked table on the goal page.

Dosage & timing

Dosage:

2000IU

Best Time:

Morning · with food

Take with food

Form:

D3 (cholecalciferol) softgel or liquid

Dosage:

180mcg

Best Time:

With meals · with food

Take with food

Form:

MK-7 (menaquinone-7)

What you'll notice

🛡️ Stronger Immunitypositive

4-8 weeks

😊 Improved Moodpositive

4-8 weeks

⚡ More Energypositive

2-4 weeks

🦴 Improved Bone Healthpositive

6-12 months

❤️ Cardiovascular Supportpositive

1-3 years

Safety

High safety

Contraindications:

Hypercalcemia
Kidney disease (consult doctor)
Sarcoidosis or other granulomatous diseases

Drug Interactions:

Thiazide diuretics
Digoxin (cardiac glycosides)
Steroids

Side Effects:

Hypercalcemia (at very high doses)GI upset

Moderate safety

Contraindications:

Those taking warfarin or other vitamin K antagonists (consult doctor)
Anticoagulant or blood thinner therapy (warfarin, heparin, Coumadin) — Vitamin K2 directly antagonizes warfarin's mechanism of action

Drug Interactions: