Supplements vergleichen

Prescription Xenical: 120 mg three times daily (360 mg/day), taken with or up to 1 hour after each main fat-containing meal. Over-the-counter Alli: 60 mg three times daily (180 mg/day). Skip the dose if a meal is missed or contains no fat. Used alongside a reduced-calorie diet in which fat supplies roughly 30% of energy — a higher-fat meal makes the gastrointestinal side effects markedly worse, not the weight loss better.

With meals · with food

Xenical 120 mg capsule three times daily with meals (prescription)

300mg standardized extract

With meals · with food

Standardisierter Extrakt (300–600 mg, 2,5 % Rosmarinsäure)

• Chronic malabsorption syndrome
• Cholestasis
• Pregnancy — intentional weight loss is not a therapeutic goal in pregnancy, and orlistat measurably lowers vitamin D and impairs vitamin E and K absorption (McDuffie 2002)

• Warfarin
• Levothyroxine (thyroxine)
• Ciclosporin (cyclosporine)

• Epilepsy or seizure disorders (thujone content may lower seizure threshold)
• Pregnancy (may stimulate uterine contractions; avoid therapeutic doses)
• Hormone-sensitive cancers (estrogenic activity; consult oncologist)

• Anticoagulants (warfarin, heparin)
• Antidiabetic drugs (metformin, insulin, sulfonylureas)
• Anticonvulsants (phenytoin, valproate, carbamazepine)