Supplements vergleichen

900mg/day standardized extract

With meals · with food

Standardisierter wässriger Extrakt (hoher Rosmarinsäuregehalt)

Approved (oncology) / off-label (male) — clinician-directed. For ER-positive breast cancer the standard adjuvant dose is 20 mg once daily for 5-10 years. For off-label male gynecomastia, the randomized trials used roughly 10-20 mg daily (10 mg/day prophylactically alongside an antiandrogen, 20 mg/day to treat established gynecomastia). For idiopathic male infertility, the trials typically used 20 mg/day. Bodybuilding 'post-cycle therapy' commonly uses 10-40 mg/day tapered — a use with no controlled-trial evidence. There is no FDA-approved male dose.

Any time

Tamoxifencitrat-Tabletten (zugelassen bei Brustkrebs; off-label bei Männern)

• Known allergy or hypersensitivity to spearmint or other Lamiaceae family plants (mint, lavender, rosemary)
• Severe gastroesophageal reflux disease (GERD) — spearmint may relax lower esophageal sphincter in some individuals
• Hormone-sensitive conditions where androgen reduction is contraindicated (consult physician)

• Hormonal contraceptives / HRT
• Anti-androgen medications (spironolactone, flutamide, finasteride)
• Iron supplements / iron-containing products

• History of venous thromboembolism (deep-vein thrombosis or pulmonary embolism) or stroke — tamoxifen raises clot risk
• Concurrent warfarin / anticoagulant therapy in the prevention setting (per label)
• Pregnancy and breastfeeding (can harm the fetus)

• Warfarin / anticoagulants
• Strong CYP2D6 inhibitors (e.g. paroxetine, fluoxetine, bupropion)
• Aromatase inhibitors / other SERMs / exogenous estrogens