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Brg2.5

Gerstengras – Forschung

Überwiegend Mechanismus / Beobachtung

6 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu Gerstengras sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus gemischt-qualitativen Studien, veröffentlicht 2002–2026 mit einer typischen Studiengröße von 36 Teilnehmenden.

Basierend auf 5 Studien · 36 Teilnehmende insgesamt

Konfidenz

Geringe Konfidenz

Nach Outcome

Glucose & metabolicEine kleine T2DM-Studie zeigte eine verringerte LDL-Oxidation; Tierdaten zeigen ein verbessertes Lipidprofil — jedoch sind metabolische Endpunkte beim Menschen nicht belegt · Unbekannt
Zu wenige bewertete Studien1 Studie

Stetige Forschung

1 Studie in den letzten 5 Jahren

200220142026

1Übersicht2026

Einfach gesagt: In conclusion, young barley preparations represent a biologically plausible functional plant food ingredient with preliminary clinical support, pending confirmation from adequately powered, standardised randomised controlled trials.

Rzeski W et al. · Molecules (Basel, Switzerland) (2026)

Agronomic variables including fertilization strategy and soil composition represent additional, underappreciated sources of phytochemical variability and safety concern.
Overall, the current evidence supports the biological plausibility of young barley as a functional plant food; yet, the clinical data remain preliminary.
Future research should prioritize preparation standardization, dose-response characterization, and agronomic transparency to strengthen translational reliability.

Quelle ansehen

2ÜbersichtRetracted2024

Einfach gesagt: Conclusion This review underscores the therapeutic potential of barley and its components in chronic disease management, highlighting the need for well-designed clinical trials to translate these findings into effective interventions.

Ali A, Ullah Z, Ullah R, Kazi M. · Heliyon (2024)

Results The finding suggests that humans digest barley starch more slowly than wheat and rice, which benefits chronic disease management.
Barley's high-molecular-weight β-glucan high content acts as a prebiotic, promotes gut health through microbiome modulation and short-chain fatty acid production, potentially preventing colon cancer and boosting immunity.
Conclusion This review underscores the therapeutic potential of barley and its components in chronic disease management, highlighting the need for well-designed clinical trials to translate these findings into effective interventions.

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3Open-Labeln=36 · small study2002

Einfach gesagt: Supplementation with young barley leaf extract helped scavenge oxygen free radicals and inhibit LDL oxidation, with the effect on small dense LDL strongest when combined with vitamins C and E.

Yu YM, Chang WC, Chang CT, Hsieh CL, Tsai CE. · Diabetes Metab (2002)

36 type 2 diabetic patients received 15g barley leaf extract, vitamins C+E, or both daily for 4 weeks (three active arms, no placebo, not randomized)
Blood chemiluminescence (free-radical) levels fell in all groups; barley leaf preserved LDL vitamin E and increased oxidation lag time
Combined barley leaf + vitamins C/E most effectively inhibited small dense LDL oxidation; small, short, single trial

4Tierstudie2019

Einfach gesagt: In high-fat-diet rats, barley grass juice reduced body weight and BMI and improved lipid profile and liver markers, with histology showing reduced atherosclerosis.

Thatiparthi J, Dodoala S, Koganti B, Kvsrg P. · J Ethnopharmacol (2019)

Barley grass juice (200 and 400 mg/kg for 60 days) reduced bodyweight, BMI and improved lipid profile and AST/ALT/ALP in high-fat-diet rats
Associated with decreased hepatic PPAR-gamma and caspase 3 expression and reduced carotid atherosclerosis; GC-MS identified 12 phytochemicals
Animal model; demonstrates plausibility, not a human effect

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5In vitro2017

Einfach gesagt: Barley grass extract inhibited breast and prostate cancer cell viability and induced apoptosis by raising intracellular reactive oxygen species in vitro.

Woo SM, Kwon SC, Ko SG, Cho SG. · Biomed Rep (2017)

Barley grass extract reduced viability of breast and prostate cancer cell lines (MTT assay)
Induced apoptosis via increased intracellular ROS, blocked by the antioxidant N-acetyl-cysteine
In-vitro cell study only; no relevance established for whole-body human outcomes

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6In vitro2011

Einfach gesagt: Ground pork containing barley leaf powder showed lower peroxide values and conjugated dienes than control, indicating the powder retarded lipid oxidation.

Choe JH, Jang A, Lee ES, et al. · Meat Sci (2011)

Barley leaf powder added to cooked ground pork at 0.1% and 0.5% lowered peroxide values and conjugated dienes versus control
Demonstrates the powder's antioxidant capacity in a food matrix
Compositional / food-science model — not a measure of any human health benefit

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In der Forschungsbibliothek ansehen

Gerstengras – Forschung

Überwiegend Mechanismus / Beobachtung

Young Barley (Hordeum vulgare L.) Preparations: From Phytochemical Complexity to Clinical Relevance

Barley a nutritional powerhouse for gut health and chronic disease defense

Effects of young barley leaf extract and antioxidative vitamins on LDL oxidation and free radical scavenging activities in type 2 diabetes.

Barley grass juice (Hordeum vulgare L.) inhibits obesity and improves lipid profile in high fat diet-induced rat model.

Barley grass extract causes apoptosis of cancer cells by increasing intracellular reactive oxygen species production.

Oxidative and color stability of cooked ground pork containing lotus leaf (Nelumbo nucifera) and barley leaf (Hordeum vulgare) powder during refrigerated storage.