Wir verwenden standardmäßig essenzielle Cookies (Anmeldung, deine gespeicherten Ziele/Stacks). Mit deiner Erlaubnis aktivieren wir außerdem datenschutzfreundliche Analytik (Vercel Web Analytics, anonyme Ladezeit-Metriken) und Fehler-Replay-Diagnostik (Sentry — DOM-Snapshots nur, wenn ein Fehler auftritt), damit wir Bugs schneller beheben können. Mehr über Cookies erfahren
Bso6.5
Black Seed Oil – Forschung
Hilft wahrscheinlich
146 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Black Seed Oil scheint in 5 von 5 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2003–2026 mit einer typischen Studiengröße von 486 Teilnehmenden.
Basierend auf 146 Studien · 33 Meta-Analysen · 68 RCTs · 25,420 Teilnehmende insgesamt
Fertility & reproductiveKann die reproduktive Gesundheit und Fertilitätsmarker unterstützen · 4-12 Wochen
Zu wenige bewertete Studien2 Studien
Joint pain & arthritis
Zu wenige bewertete Studien2 Studien
Anxiety & stress
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 45 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
100%
über Studien hinweg
Untersuchte Personen
25k
typische Studie: 486 Personen
Stärkste Designs
101
33 gepoolt, 68 randomisiert
Zeigte Nutzen
100%
5/5 Studien
Wie lange Studien liefen
1–3 Monate
2
Untersuchte Populationen
General population4
Metabolic syndrome patients2
COVID-19 patients2
Functional dyspepsia patients1
Aktives Forschungsgebiet
81 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026
200320142026
1Global symptoms of dyspepsiaSystematische Übersichtn=4,477 · very large study2023
Einfach gesagt: Based on moderate to very low-certainty evidence, we identified some herbal medicines that may be effective in improving symptoms of dyspepsia.
Báez G et al. · The Cochrane database of systematic reviews (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
STW5 (Iberogast) may moderately improve global symptoms of dyspepsia compared with placebo at 28 to 56 days; however, the evidence is very uncertain (MD -2.64, 95% CI -4.39 to -0.90; I2 = 87%; 5 studies, 814 participants; very low CoE).
STW5 may also increase the improvement rate compared to placebo at four to eight weeks' follow-up (RR 1.55, 95% CI 0.98 to 2.47; 2 studies, 324 participants; low CoE).
There was little to no difference in adverse events for STW5 compared to placebo (RR 0.92, 95% CI 0.52 to 1.64; I2 = 0%; 4 studies, 786 participants; low CoE).
2Body weight reductionMeta-Analysen=6,171 · very large study2023
Einfach gesagt: We conducted random-effects network meta-analysis with a Frequentist framework to estimate mean difference [MD] and 95% confidence interval [CI] of the effect of nutraceuticals on weight loss.
Shahinfar H et al. · Pharmacological research (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
We conducted random-effects network meta-analysis with a Frequentist framework to estimate mean difference [MD] and 95% confidence interval [CI] of the effect of nutraceuticals on weight loss.
Supplementations with green tea (MD: -1.25 kg, 95%CI: -1.68, -0.82) and glucomannan (MD: -1.36 kg, 95%CI: -2.17, -0.54) demonstrated small weight loss, also the certainty of evidence was rated low.
Based on our findings, supplementations with nutraceuticals can result in a small weight loss in adults with overweight or obesity.
3Cholesterol levelsMeta-Analysen=1,386 · large study2021
Einfach gesagt: In addition, minimal evidence was found for any side effects associated with these herbs, positioning them as safe adjuvants to conventional treatments.
Gyawali D et al. · Medicina (Kaunas, Lithuania) (2021)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Meta-analysis of the trials showed that guggulu reduced total cholesterol and low-density lipoprotein levels by 16.78 mg/dL (95% C.I. 13.96 to 2.61; p-value = 0.02) and 18.78 mg/dL (95% C.I. 34.07 to 3.48; p = 0.02), respectively.
Garlic reduced LDL-C by 10.37 mg/dL (95% C.I. -17.58 to -3.16; p-value = 0.005).
Black cumin lowered total cholesterol by 9.28 mg/dL (95% C.I. -17.36, to -1.19, p-value = 0.02).
4Idiopathic male infertility treatmentSystematische Übersichtn=1,218 · large study2022
Einfach gesagt: Whitania somnifera roots, Alpinia officinarum, Nigella sativa seeds, Tomato, and Ceratonia siliqua and the formulation of Xperm, PHF, Churna Ratnam, Svaguptadi Churna, Y virilin capsule, manix capsule, and Tradafertil tablet revealed successful outcomes in treatment of idiopathic male infertility.
Ahmadian M et al. · Current drug discovery technologies (2022)
Whitania somnifera roots, Alpinia officinarum, Nigella sativa seeds, Tomato, and Ceratonia siliqua and the formulation of Xperm, PHF, Churna Ratnam, Svaguptadi Churna, Y virilin capsule, manix capsule, and Tradafertil tablet revealed successful outcomes in treatment of idiopathic male infertility.
7Hypothyroidism treatmentSystematische Übersichtn=186 · medium study2023
Einfach gesagt: Some herbal remedies, including Nigella sativa L., ashwagandha, and Mentha x Piperita L., can improve the signs and symptoms of primary hypothyroidism, but using a more extensive and advanced methodology will provide us with more complete results.
Javidi N et al. · Current drug discovery technologies (2023)
Likely real
In one study, Nigella sativa L. caused a significant decrease in weight (P=0.004) and body mass index (BMI) (P=0.002).
TSH levels were reported to be decreased and T3 increased in the treatment group (P =0.03) (P=0.008), respectively.
In another study on Nigella sativa L., results did not show a significant difference between the two groups (p=0.02).
13Glycemic status improvementMeta-Analysen=30 · small study2024
Einfach gesagt: Random effects models were assessed based on the heterogeneity tests, and pooled data were determined as weighted mean differences with a 95 % confidence interval.
Shirvani S et al. · Prostaglandins & other lipid mediators (2024)
Random effects models were assessed based on the heterogeneity tests, and pooled data were determined as weighted mean differences with a 95 % confidence interval.
Finally, a total of 30 studies were found to be eligible for this meta-analysis.
Additional research, featuring extended durations and robust study designs, is necessary to determine the ideal dosage and duration of N. sativa supplementation for achieving a positive impact on glycemic markers.
Einfach gesagt: Current evidence supports the use of ginger and turmeric for glycaemic control in type 2 diabetes, however, given the high clinical heterogeneity and low quality of the review, our confidence in this finding is somewhat limited.
Li E et al. · BMC complementary medicine and therapies (2025)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Ginger, turmeric, and Jinlida granules significantly decreased HbA1c compared to placebo (mean differences (MD): -0.467%, -0.486%, -0.283%, respectively) with moderate to high certainty evidence.
Current evidence supports the use of ginger and turmeric for glycaemic control in type 2 diabetes, however, given the high clinical heterogeneity and low quality of the review, our confidence in this finding is somewhat limited.
Herbal medicines should be used only as an adjunct to conventional treatment, with shared decision-making between clinicians and patients.
20Cardiometabolic indices improvementMeta-Analyse2025
Einfach gesagt: Black seed supplementation appears to significantly improve FBG, HbA1c, TC, and LDL levels in patients with T2DM.
Karimi M et al. · Complementary therapies in medicine (2025)
Black seed supplementation appears to significantly improve FBG, HbA1c, TC, and LDL levels in patients with T2DM.
However, no significant effects were observed on other metabolic parameters, including insulin, TG, liver enzymes, kidney function, or body weight.
These findings suggest that black seed may be a beneficial adjunct therapy for glycemic and lipid control in T2DM patients but require further research to confirm its broader metabolic effects.