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Bdw2.5

Bladderwrack – Forschung

Überwiegend Mechanismus / Beobachtung

5 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu Bladderwrack sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus mittelwertigen randomisierten Studien, veröffentlicht 1999–2024 mit einer typischen Studiengröße von 12 Teilnehmenden.

Basierend auf 5 Studien · 2 RCTs · 80 Teilnehmende insgesamt

Konfidenz

Geringe Konfidenz

Nach Outcome

Glucose & metabolicVermutete glykämische/metabolische Unterstützung durch Fucoidan und Polyphenole (nur in Kombinationsprodukten gezeigt, nicht durch Blasentang allein) · Unbekannt
Zu wenige bewertete Studien2 Studien

Stetige Forschung

1 Studie in den letzten 5 Jahren

199920112024

1RCTn=12 · very small study2024

Einfach gesagt: Discussion A daily intake of 5 g of fresh, dried S. fusiforme or F. vesiculosus alongside regular treatment had no differential effect on weekly average blood glucose levels in T2DM.

Geurts KAM, Meijer S, Roeters van Lennep JE, Wang X, Özcan B, Voortman G, Liu H, Castro Cabezas M, Berk KA, Mulder MT. · Nutrients (2024)

Results The change in weekly average glucose levels was 8.2 ± 2.1 to 9.0 ± 0.7 mmol/L ( p = 0.2) in the S. fusiforme group (n = 12) and 10.1 ± 3.3 to 9.2 ± 0.7 mmol/L ( p = 0.9) in the F. vesiculosus group (n = 10).
The between-group difference was non-significant.
Similarly, no between-group differences were observed for the changes in the secondary outcomes.

Quelle ansehen

2RCTn=65 · small study2019

Einfach gesagt: A nutraceutical combining Ascophyllum and Fucus polyphenols with chromium picolinate improved insulin sensitivity and glycemic status — but larger studies are required to confirm.

Derosa G, Cicero AFG, D'Angelo A, Maffioli P. · Phytother Res (2019)

Combination of Fucus + Ascophyllum polyphenols + chromium picolinate reduced HbA1c, fasting and postprandial glucose, and HOMA-IR vs placebo
Effect cannot be attributed to bladderwrack alone — it was a multi-ingredient product including chromium
Authors explicitly state larger randomized studies are needed

Quelle ansehen

3Beobachtungsstudie1999

Einfach gesagt: Regular consumption of algae, especially Laminaria species, could result in iodine levels sufficient to cause thyroid problems; Fucus was among the seaweeds analyzed.

Phaneuf D, Côté I, Dumas P, Ferron LA, LeBlanc A. · Environ Res (1999)

Analyzed Fucus vesiculosus and other seaweeds for metals (including arsenic, cadmium, lead) and iodine
Iodine-thyroid risk was flagged primarily for high-iodine Laminaria species; Fucus vesiculosus was among the seaweeds analyzed for contaminants
Recommends choosing low-iodine species for frequent consumption

Quelle ansehen

4Tierstudie2011

Einfach gesagt: Fucoidan from Fucus showed antithrombin and anti-factor Xa activity, with both antithrombotic and hemorrhagic (bleeding) activity increasing with dose.

Drozd NN, Miftakhova NT, Savchik EIu, et al. · Eksp Klin Farmakol (2011)

Fucoidan from a Fucus species had measurable antithrombin and anti-factor Xa activity
Both antithrombotic and hemorrhagic activity rose with dose in rats
Mechanistic basis for a plausible bleeding-risk interaction in humans

5Fallstudien=3 · very small study2004

Einfach gesagt: These pilot data suggest dietary bladderwrack may prolong menstrual cycle length and exert anti-estrogenic effects, but well-controlled clinical trials are needed to confirm.

Skibola CF. · BMC Complement Altern Med (2004)

Only three pre-menopausal women — a case report, not a controlled trial
Associated with longer menstrual cycles and, in one woman, lower estradiol and higher progesterone
Hypothesis-generating only; author calls explicitly for controlled trials

Quelle ansehen

In der Forschungsbibliothek ansehen

Bladderwrack – Forschung

Überwiegend Mechanismus / Beobachtung

The Effect of Sargassum fusiforme and Fucus vesiculosus on Continuous Glucose Levels in Overweight Patients with Type 2 Diabetes Mellitus: A Feasibility Randomized, Double-Blind, Placebo-Controlled Trial

Ascophyllum nodosum and Fucus vesiculosus on glycemic status and on endothelial damage markers in dysglicemic patients.

Evaluation of the contamination of marine algae (seaweed) from the St. Lawrence River and likely to be consumed by humans.

[Antithrombotic and hemorrhagic activities of fucoidan isolated from Fucus evanescens brown algae].

The effect of Fucus vesiculosus, an edible brown seaweed, upon menstrual cycle length and hormonal status in three pre-menopausal women: a case report.