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Dgl4.5

DGL Licorice – Forschung

Überwiegend Mechanismus / Beobachtung

95 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu DGL Licorice sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1965–2026 mit einer typischen Studiengröße von 83 Teilnehmenden.

Basierend auf 95 Studien · 9 Meta-Analysen · 78 RCTs · 461 Teilnehmende insgesamt

Konfidenz

Hohe Konfidenz

Nach Outcome

Digestive & gastric mucosaEine kleine RCT linderte funktionelle Dyspepsie; die Evidenz zu Reflux/Ulkus ist dünn und veraltet · 2-4 weeks
Überwiegend Mechanismus / Beobachtung25 Studien
Oral & dental health
Überwiegend Mechanismus / Beobachtung14 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung5 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung5 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung4 Studien
Liver health
Zu wenige bewertete Studien2 Studien

Stetige Forschung

28 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2024

196519952026

1H. pylori eradication ratesMeta-Analyse2023

Polyphenol compounds plus standard triple therapy can significantly improve the eradication.

Wang Q et al. · BMJ Open (2023)

Meta-analysis of polyphenol compounds including liquorice for H. pylori eradication (12 RCTs)
Overall eradication rate was higher with polyphenol compounds (RR 1.19, 95% CI 1.03 to 1.38, p=0.02)
Polyphenols plus triple therapy outperformed triple therapy alone (RR 1.11, 95% CI 1.01 to 1.22, p=0.03), with no increase in side effects

DGL Licorice – Forschung

Überwiegend Mechanismus / Beobachtung

Effect of polyphenol compounds on Helicobacter pylori eradication: a systematic review with meta-analysis

Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology

Licorice and liver function in patients with primary liver disease: A systematic review and meta-analysis of RCTs.

Effects of Licorice Functional Components Intakes on Blood Pressure: A Systematic Review with Meta-Analysis and NETWORK Toxicology.

Preclinical studies of licorice in ulcerative colitis: A systematic review with meta-analysis and network pharmacology.

Topical application of licorice for prevention of postoperative sore throat in adults: A systematic review and meta-analysis.

Identification of glycyrrhizin metabolites in humans and of a potential biomarker of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study.

Metabolic changes after licorice consumption: A systematic review with meta-analysis and trial sequential analysis of clinical trials.

The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis.

Herbal medicine (Gan Mai Da Zao decoction) for depression: a systematic review and meta-analysis of randomized controlled trials.

Topical Licorice for Aphthous: A Systematic Review of Clinical Trials.

Licorice (Glycyrrhiza spp.) and jujube (Ziziphus jujuba Mill.) formula for menopausal symptoms: Classical records, clinical evidence and experimental data.

Isolation, structural characterization, biological activity, and application of Glycyrrhiza polysaccharides: Systematic review.

Effectiveness of licorice in preventing dental caries in children: A systematic review.

Efficacy of Licorice Lollipops in Reducing Dental Caries in a Paediatric Population: A Systematic Review.

A Systematic Review of the Anticancer Properties of Compounds Isolated from Licorice (Gancao).

Efficacy and immunomodulatory effects of licorice nasal spray in allergic rhinitis: A clinical study comparing with conventional steroid treatment.

A Comparative evaluation of locally delivered licorice gel and tetracycline gel as an adjunct to non-surgical therapy in the treatment of controlled type -2 diabetic patients with periodontitis stage II and grade B - A split mouth randomized clinical trial.

Effectiveness of Glycyrrhiza uralensis extract on periodontal pathogens: a randomized controlled clinical trial.

Effects of licorice extract in combination with a low-calorie diet on obesity indices, glycemic indices, and lipid profiles in overweight/obese women with polycystic ovary syndrome (PCOS): a randomized, double-blind, placebo-controlled trial.