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Fen6.0
Fenugreek – Forschung
Hilft wahrscheinlich
82 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Fenugreek scheint in 11 von 12 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2001–2026 mit einer typischen Studiengröße von 82 Teilnehmenden.
Basierend auf 82 Studien · 21 Meta-Analysen · 32 RCTs · 12,709 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
11geholfen1unklar· 70 weitere ohne bewertete Effektdaten
Nach Outcome
Women's healthUnterstützt einen gesunden Östrogenstoffwechsel und das hormonelle Gleichgewicht · 4-8 weeks · Kann helfen, Menstruationsbeschwerden und PMS-Symptome zu reduzieren · 1-3 cycles · Reduzierte postprandiale Glukosespitzen · 4-8 weeks
Hilft wahrscheinlich33 Studien
Glucose & metabolicVerbessert die postprandiale Glukoseantwort und Lipidmarker · 8-12 weeks · Improves post-meal glucose response and lipid markers · 8-12 weeks
Hilft wahrscheinlich26 Studien
Men's vitalityBlutzuckerstabilisierung unterstützt anhaltende Energie · 2-4 weeks
Überwiegend Mechanismus / Beobachtung11 Studien
Cholesterol & lipids
Überwiegend Mechanismus / Beobachtung7 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung7 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung6 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung6 Studien
InflammationHemmt Aromatase und 5-alpha-Reduktase zur Modulation des Testosterons · 4-8 weeks
Zu wenige bewertete Studien2 Studien
Lean body mass & muscle growthVerbesserte Blutzuckerkontrolle · 4-12 weeks
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 33 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
50%
über Studien hinweg
Untersuchte Personen
13k
typische Studie: 82 Personen
Stärkste Designs
53
21 gepoolt, 32 randomisiert
Zeigte Nutzen
92%
11/12 Studien
Wie lange Studien liefen
1–4 Wochen
1
1–3 Monate
3
3+ Monate
1
Untersuchte Populationen
Type 2 diabetes patients3
Adults3
Diabetes patients2
Men2
Aktives Forschungsgebiet
42 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2024
200120132026
1Fasting blood glucoseMeta-Analysen=3,130 · very large study2023
Einfach gesagt: Several herbs could be considered as a valuable adjuvant therapy regarding glycemic control of type 2 diabetes patients.
Kumar S et al. · Diabetes & metabolic syndrome (2023)
Sehr groß Nutzen
← SchlechterKein EffektBesser →
Apple cider vinegar (ACV) (standardized mean difference (SMD) = -28.99), cinnamon (-9.73), curcumin (-13.15), and fenugreek (-19.64) significantly reduced fasting blood glucose (FBG) compared with placebo (all p < 0.05).
Notably, only ACV (SMD = -2.10) and fenugreek seeds (0.84) were found significantly effective in reducing HbA1C.
Several herbs could be considered as a valuable adjuvant therapy regarding glycemic control of type 2 diabetes patients.
2Fasting blood glucoseMeta-Analysen=894 · large study2023
Einfach gesagt: Given the wider availability and lower cost of fenugreek, rigorous double-blinded randomized controlled trials should be conducted with fenugreek to understand its true potential as a diabetes control herbal agent.
Shabil M et al. · Medicina (Kaunas, Lithuania) (2023)
Kein klarer Effekt
← SchlechterKein EffektBesser →
Could be chance
The mean difference with 95% confidence intervals (CI) was calculated to represent the analysis.
The results showed a reduction in fasting blood glucose levels (MD: 3.70, 95% CI of -27.02, 19.62; p = 0.76), postprandial blood glucose (MD: -10.61, 95% CI of -68.48, 47.26; p = 0.72), and HbA1c (MD: -0.88, 95% CI -1.49, -0.27; p = 0.00) with fenugreek consumption.
Fourteen trials, consisting of 894 participants, were included in the meta-analysis.
3Dysmenorrhoea symptomsMeta-Analysen=3,101 · very large study2016
Einfach gesagt: There is no high quality evidence to support the effectiveness of any dietary supplement for dysmenorrhoea, and evidence of safety is lacking.
Pattanittum P et al. · The Cochrane database of systematic reviews (2016)
Supplements versus other supplementsThere was no evidence of a difference in effectiveness between ginger and zinc sulphate (MD 0.02 points, 95% CI -0.58 to 0.62; one RCT, 101 women).
Vitamin B1 may be more effective than fish oil (MD -1.59 points, 95% CI -2.25 to -0.93; one RCT, 120 women).
There is no high quality evidence to support the effectiveness of any dietary supplement for dysmenorrhoea, and evidence of safety is lacking.
6Systolic blood pressureMeta-Analysen=373 · medium study2023
Einfach gesagt: Supplementation with fenugreek seed, especially in dosages ≥ 15 g/day and durations ≤ 12 weeks, might play a role in reducing SBP, but not DBP.
Amini MR et al. · High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Fenugreek seed supplementation significantly reduced SBP (WMD: 3.46 mmHg, 95% CI - 6.33, - 0.59, P=0.018), but not DBP (WMD: 3.19 mmHg; 95% CI, - 5.82 to 12.21, P=0.488).
Subgroup analyses showed that fenugreek seed administered in dosages ≥ 15 g/day and durations ≤ 12 weeks significantly reduced SBP and DBP.
However, further investigations are warranted to ensure the clinical relevance of these findings.
10Glycemic controlMeta-Analysen=487 · medium study2011
Einfach gesagt: The current evidence suggests that supplementation with Ipomoea batatas, Silybum marianum, and Trigonella foenum-graecum may improve glycemic control in type 2 diabetes.
Suksomboon N et al. · Journal of ethnopharmacology (2011)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Ipomoea batatas, Silybum marianum and Trigonella foenum-graecum significantly improved glycemic control, whereas Cinnamomum cassia did not.
The pooled mean differences in HbA(1c) were -0.30% (95% CI -0.04% to -0.57%; P = 0.02), -1.92% (95% CI -0.51% to -3.32%; P = 0.008), and -1.13% (95% CI -0.11% to -2.14%; P = 0.03), respectively, for Ipomoea batatas, Silybum marianum, and Trigonella foenum-graecum.
The corresponding values for FBG were -10.20mg/dL (95% CI -5.32 mg/dL to -15.08 mg/dL; P<0.0001) and -38.05 mg/dL (95% CI -9.54 mg/dL to -66.57 mg/dL; P = 0.009), respectively, for Ipomoea batatas and Silybum marianum.
11Weight reductionMeta-Analysen=279 · medium study2020
Einfach gesagt: High quality trials are still needed to firmly establish the clinical efficacy of the plants in obesity and metabolic syndrome.
Payab M et al. · Phytotherapy research : PTR (2020)
Sehr groß Nutzen
← SchlechterKein EffektBesser →
Pooled effect of herbal medicines on obesity and metabolic syndrome were presented as standardized mean difference (SMD) and 95% confidence interval (CI).
In addition, the intake of P. vulgaris and N. sativa resulted in a significant improvement in weight ([SMD]: -0.88, 95 % CI: [-1.13, -0.63]) and triglyceride ([SMD]: -1.67, 95 % CI: [-2.54, -0.79]), respectively.
In addition, C. fimbriata, flaxseed, spinach, and fenugreek were able to reduce appetite.
12Breast milk productionMeta-Analysen=122 · medium study2018
Einfach gesagt: The NMA using pairwise comparison demonstrated the effect of C. amboinicus and palm date in the stimulation of the breast milk production was comparable and superior to all comparators.
Khan TM et al. · Phytotherapy research : PTR (2018)
Spürbar Nutzen
← SchlechterKein EffektBesser →
League tables were generated using treatment effect, weighted mean difference (WMD; 95% confidence interval, CI) for all pairwise comparisons, where WMD > 0 favors the column-defining treatment.
The NMA results of 4 studies indicated that consumption of fenugreek significantly increased amount of the produced breast milk [11.11, CI 95% 6.77, 15.46] versus placebo.
The pairwise comparison revealed that fenugreek was effective as a galactagogue compared to placebo, control, and reference groups WMD 17.79 [CI 11.71, 23.88].
Einfach gesagt: The evidence presented in the current systematic review indicates that flour-derived foods intake is related to improve cardiometabolic risk factors parameters.
de Souza LVM et al. · Critical reviews in food science and nutrition (2024)
Chia flour, green banana flour, soy flour, and fenugreek powder showed improvements in blood pressure measurements.
Brazil nut flour and chia flour reduced total cholesterol.
Einfach gesagt: Further high-quality studies should be conducted to establish the clinical efficacy of herbal medicines.
Correia AGDS et al. · Phytotherapy research : PTR (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Could be chance
The mean difference (MD) and the standardized MD (SMD) were adopted, and subgroup analyses were performed according to patient's clinical condition.
Saffron supplementation reduced FBG (MD: -9.06 mg/dl; 95%CI: -16.25 to -1.86; I2 = 40%; p = 0.12) and HbA1c (MD: -0.19%; 95%CI: -0.23 to -0.14; I2 = 0%; p > 0.99).
Our results show that using saffron and fenugreek can reduce FBG, PPBG, and HbA1c; however, there are some shortcomings that require attention for these results.
16Testosterone concentrationsSystematische Übersichtn=32 · small study2021
Einfach gesagt: Overall, 9 out of 32 studies demonstrated statistically significant increases in testosterone concentrations.
Smith SJ et al. · Advances in nutrition (Bethesda, Md.) (2021)
Groß Nutzen
← SchlechterKein EffektBesser →
Overall, 9 out of 32 studies demonstrated statistically significant increases in testosterone concentrations.
Conclusions are moderated by the paucity of research for many herbs, the variation in dosages and extracts used, small sample sizes, and the heterogeneity of study characteristics.
Also, further research is required before definitive conclusions on efficacy and safety can be made.
Einfach gesagt: Further high-quality studies are needed to firmly establish the clinical efficacy of the plant.
Heshmat-Ghahdarijani K et al. · Phytotherapy research : PTR (2020)
The pooled weighted mean difference (MD) and its 95% confidence interval (CI) were calculated and pooled using a random-effect model.
There were no significant differences in TC, TG, and LDL between pre- and post-fenugreek studies in the noncontrolled studies however, the result of combination of four studies without control group showed a significant increase in mean HDL (0.81 [0.33,1.29]; p-value = .001).