Wir verwenden standardmäßig essenzielle Cookies (Anmeldung, deine gespeicherten Ziele/Stacks). Mit deiner Erlaubnis aktivieren wir außerdem datenschutzfreundliche Analytik (Vercel Web Analytics, anonyme Ladezeit-Metriken) und Fehler-Replay-Diagnostik (Sentry — DOM-Snapshots nur, wenn ein Fehler auftritt), damit wir Bugs schneller beheben können. Mehr über Cookies erfahren
Gm6.5
Glucomannan – Forschung
Hilft wahrscheinlich
74 begutachtete Studien
Was die Evidenz sagt
Hilft wahrscheinlich
Glucomannan scheint in 8 von 9 Studien mit messbaren Effekten zu helfen — die Evidenz tendiert klar ins Positive.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1984–2026 mit einer typischen Studiengröße von 53 Teilnehmenden.
Basierend auf 74 Studien · 9 Meta-Analysen · 53 RCTs · 8,845 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
8geholfen1unklar· 65 weitere ohne bewertete Effektdaten
Nach Outcome
Weight managementSättigung und verminderte Kalorienaufnahme · 4-8 Wochen
Hilft wahrscheinlich65 Studien
Cholesterol & lipids
Hilft wahrscheinlich62 Studien
Glucose & metabolicVerlangsamt die Glukoseaufnahme und verbessert das Lipidprofil · 4-12 Wochen
Hilft wahrscheinlich62 Studien
Digestive healthPräbiotische Ballaststoffe fördern eine gesunde Darmfunktion und das Mikrobiom · 1-2 Wochen
Hilft wahrscheinlich61 Studien
Heart & blood pressure
Zu wenige bewertete Studien2 Studien
Therapeutic & clinical
Zu wenige bewertete Studien2 Studien
In Zahlen
Aus 27 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
100%
über Studien hinweg
Untersuchte Personen
8,845
typische Studie: 53 Personen
Stärkste Designs
62
9 gepoolt, 53 randomisiert
Zeigte Nutzen
89%
8/9 Studien
Wie lange Studien liefen
1–4 Wochen
3
1–3 Monate
2
3+ Monate
2
Untersuchte Populationen
Adults2
Adults with obesity2
Healthy adults2
Type 2 diabetes mellitus patients2
Stetige Forschung
22 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2025
198420052026
1Body weight reductionMeta-Analysen=6,171 · very large study2023
Einfach gesagt: We conducted random-effects network meta-analysis with a Frequentist framework to estimate mean difference [MD] and 95% confidence interval [CI] of the effect of nutraceuticals on weight loss.
Shahinfar H et al. · Pharmacological research (2023)
Spürbar Nutzen
← SchlechterKein EffektBesser →
We conducted random-effects network meta-analysis with a Frequentist framework to estimate mean difference [MD] and 95% confidence interval [CI] of the effect of nutraceuticals on weight loss.
Supplementations with green tea (MD: -1.25 kg, 95%CI: -1.68, -0.82) and glucomannan (MD: -1.36 kg, 95%CI: -2.17, -0.54) demonstrated small weight loss, also the certainty of evidence was rated low.
Based on our findings, supplementations with nutraceuticals can result in a small weight loss in adults with overweight or obesity.
3Type II diabetes managementMeta-Analysen=440 · medium study2023
Einfach gesagt: Our analysis indicates that glucomannan is an effective nutritional intervention for type II diabetes.
Zhang Z et al. · Nutrients (2023)
We searched databases including PubMed, Cochrane, the comprehensive biomedical research database (Embase), Web of Science, and China National Knowledge Infrastructure (CNKI) for literature on glucomannan and type II diabetes.
Six randomized controlled trials (RCTs) were eligible (n = 440 participants) to be included in our analysis.
Our analysis indicates that glucomannan is an effective nutritional intervention for type II diabetes.
Einfach gesagt: While some dietary supplements containing isolated organic compounds warrant further investigation to determine efficacy and safety, there is currently insufficient evidence to recommend any of these dietary supplements for weight loss.
Bessell E et al. · International journal of obesity (2005) (2021)
There was no statistically significant effect on weight for fructans compared to placebo (p = 0.24).
While some dietary supplements containing isolated organic compounds warrant further investigation to determine efficacy and safety, there is currently insufficient evidence to recommend any of these dietary supplements for weight loss.
Einfach gesagt: The evidence from available RCTs does not show that glucomannan intake generates statistically significant weight loss.
Onakpoya I et al. · Journal of the American College of Nutrition (2014)
Kein klarer Effekt
← SchlechterKein EffektBesser →
A meta-analysis (random effect model) of 8 RCTs revealed a nonstatistically significant difference in weight loss between glucomannan and placebo (mean difference [MD]: -0.22 kg; 95% confidence interval [CI], -0.62, 0.19; I(2) = 65%).
The evidence from available RCTs does not show that glucomannan intake generates statistically significant weight loss.
Future trials should be more rigorous and better reported.
13Weight management and metabolic indicatorsÜbersicht2026
Einfach gesagt: This review emphasized the need for purpose-driven supplement selection that integrates efficacy, safety, usage context, and evidence level, and the importance of consumers' critical information appraisal capacity, supported by structured information provision and education.
Lee H et al. · Nutrients (2026)
PubMed, MEDLINE, and Google Scholar databases were searched for studies published between 1 January 2020 and 10 October 2025.
Although some studies have reported improvements in weight and metabolic indicators, consistent scientific evidence has not yet been established.
This review emphasized the need for purpose-driven supplement selection that integrates efficacy, safety, usage context, and evidence level, and the importance of consumers' critical information appraisal capacity, supported by structured information provision and education.
16Body weight reductionRCTn=112 · medium study2024
Einfach gesagt: Dietary supplementation with glucomannan, inulin, and psyllium effectively promotes weight loss and improves body composition in individuals with obesity, particularly those with specific genetic polymorphisms.
Pokushalov E et al. · Nutrients (2024)
Kaum spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
The experimental group showed significant reductions in body weight (treatment difference: -4.9%; 95% CI: -6.9% to -2.9%; p < 0.01) and BMI (treatment difference: -1.4 kg/m2; 95% CI: -1.7 to -1.2; p < 0.01) compared to placebo.
Further significant decreases in fat mass (treatment difference: -13.0%; 95% CI: -14.4 to -11.7; p < 0.01) and visceral fat rating (treatment difference: -1.3; 95% CI: -1.6 to -1.0; p < 0.01) were noted.
Homozygous minor allele carriers experienced greater decreases in body weight (treatment difference: -3.2%; 95% CI: -4.9% to -1.6%; p < 0.01) and BMI (treatment difference: -1.2 kg/m2; 95% CI: -2.0 to -0.4; p < 0.01) compared to heterozygous allele carriers.
17Glycaemic response and satiationCrossovern=16 · very small study2025
Einfach gesagt: These novel findings suggest that SB can modulate insulin response and influence appetite regulation, highlighting its potential use in weight management strategies.
Ancu O et al. · European journal of nutrition (2025)
SBD intake significantly reduced the insulin concentration compared to dextrose alone at 45, 75, and 90 min post-intake.
These novel findings suggest that SB can modulate insulin response and influence appetite regulation, highlighting its potential use in weight management strategies.
18Gastrointestinal symptoms in functional constipationRCTn=66 · small study2025
Einfach gesagt: Konjac glucomannan significantly ameliorated gastrointestinal symptoms in elite athletes with functional constipation, potentially via modulation of the gut microbiota.
Zhu Y et al. · European journal of nutrition (2025)
Compared to the placebo group, the KGM group exhibited significant improvements in PAC-SYM, PAC-QoL, BMF, and BFI scores (p < 0.05 for all).
Konjac glucomannan significantly ameliorated gastrointestinal symptoms in elite athletes with functional constipation, potentially via modulation of the gut microbiota.