MitoQ – Forschung

The Effect of MitoQ on Aging-Related Biomarkers: A Systematic Review and Meta-Analysis.

Braakhuis AJ, Nagulan R, Somerville V · Oxid Med Cell Longev (2018)

Effect of mitochondrial-targeted antioxidants on glycaemic control, cardiovascular health, and oxidative stress in humans: A systematic review and meta-analysis of randomized controlled trials.

Mason SA, Wadley GD, Keske MA, Parker L · Diabetes Obes Metab (2022)

Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study.

Kronborg TM, Ytting H, Hobolth L, Møller S, Kimer N · Front Med (Lausanne) (2021)

Coenzyme Q10 Supplementation and Its Impact on Exercise and Sport Performance in Humans: A Recovery or a Performance-Enhancing Molecule?

Drobnic F, Lizarraga MA, Caballero-García A, Cordova A · Nutrients (2022)

The mitochondria-targeted antioxidant MitoQ, attenuates exercise-induced mitochondrial DNA damage.

Williamson J, Hughes CM, Cobley JN, Davison GW · Redox Biol (2020)

MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men.

Broome SC, Pham T, Braakhuis AJ, Narang R, Wang HW, Hickey AJR · Redox Biol (2022)

Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress.

Murray KO, Ludwig KR, Darvish S, Coppock ME, Seals DR, Rossman MJ · Am J Physiol Heart Circ Physiol (2023)

Acute mitochondrial antioxidant intake improves endothelial function, antioxidant enzyme activity, and exercise tolerance in patients with peripheral artery disease.

Park SY, Pekas EJ, Headid RJ, Son WM, Wooden TK, Song J · Am J Physiol Heart Circ Physiol (2020)

Effect of Combined Endurance Training and MitoQ on Cardiac Function and Serum Level of Antioxidants, NO, miR-126, and miR-27a in Hypertensive Individuals.

Masoumi-Ardakani Y, Najafipour H, Nasri HR, Aminizadeh S, Jafari S, Moflehi D · Biomed Res Int (2022)

Mitochondria-specific antioxidant supplementation does not influence endurance exercise training-induced adaptations in circulating angiogenic cells, skeletal muscle oxidative capacity or maximal oxygen uptake.

Shill DD, Southern WM, Willingham TB, Lansford KA, McCully KK, Jenkins NT · J Physiol (2016)

Mitochondrial-targeted antioxidant ingestion acutely blunts VO2max in physically inactive females.

Hughes RP, Carlini NA, Fleenor BS, Harber MP · Physiol Rep (2023)

Effects of a mitochondrial-targeted ubiquinol on vascular function and exercise capacity in chronic kidney disease: a randomized controlled pilot study.

Kirkman DL, Stock JM, Shenouda N, Bohmke NJ, Kim Y, Kidd J · Am J Physiol Renal Physiol (2023)

Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults.

Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL · Hypertension (2018)

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients.

Gane EJ, Weilert F, Orr DW, Keogh GF, Gibson M, Lockhart MM · Liver Int (2010)

Eight weeks of MitoQ supplementation does not alter kidney function or urinary kidney injury biomarkers in middle-aged and older adults.

Stute NL, Muma JP, Hutchison ZJ, Culver MN, Linder BA, Sanchez SO · Am J Physiol Renal Physiol (2026)

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease.

Snow BJ, Rolfe FL, Lockhart MM, Frampton CM, O'Sullivan JD, Fung V · Mov Disord (2010)

Mitochondria-targeted antioxidant supplementation does not affect muscle soreness or recovery of maximal voluntary isometric contraction force following muscle-damaging exercise in untrained men: a randomized clinical trial.

Broome SC, Atiola RD, Braakhuis AJ, Mitchell CJ, Merry TL · Appl Physiol Nutr Metab (2022)

Mitochondria-targeted antioxidant supplementation improves 8 km time trial performance in middle-aged trained male cyclists.

Broome SC, Braakhuis AJ, Mitchell CJ, Merry TL · J Int Soc Sports Nutr (2021)

Effects of Mitoquinone (MitoQ) Supplementation on Aerobic Exercise Performance and Oxidative Damage: A Systematic Review and Meta-analysis

Einfach gesagt: Future research should investigate whether MitoQ supplementation concurrent with exercise training (e.g., 4-16 weeks) alters adaptations induced by exercise alone and using different doses.

Gonzalo-Skok O, Casuso RA. · Sports medicine - open (2024)

Beyond Supportive Care: Mitochondria as a Strategic Therapeutic Avenue in Acute Pancreatitis

Einfach gesagt: Mitochondria-targeted therapies offer a mechanistically grounded strategy to reduce AP severity.

Chooklin S et al. · Digestive diseases and sciences (2026)