Oxymetholone (Anadrol) – Forschung

Oxymetholone promotes weight gain in patients with advanced human immunodeficiency virus (HIV-1) infection.

Hengge UR, Baumann M, Maleba R, Brockmeyer NH, Goos M · Br J Nutr (1996)

Immunosuppressive therapy of aplastic anemia: results of a prospective, randomized trial of antithymocyte globulin (ATG), methylprednisolone, and oxymetholone to ATG, very high-dose methylprednisolone, and oxymetholone.

Doney K, Pepe M, Storb R, Bryant E, Anasetti C, Appelbaum FR · Blood (1992)

Effects of an oral androgen on muscle and metabolism in older, community-dwelling men.

Schroeder ET, Singh A, Bhasin S, Storer TW, Azen C, Davidson T · Am J Physiol Endocrinol Metab (2003)

Effect of lithium carbonate plus oxymetholone vs. lithium alone on chemotherapy-induced myelosuppression.

Steinherz PG, Rosen G, Miller DR · Am J Pediatr Hematol Oncol (1983)

Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting.

Hengge UR, Stocks K, Wiehler H, Faulkner S, Esser S, Lorenz C · AIDS (2003)

Effect of oral anabolic steroid on muscle strength and muscle growth in hemodialysis patients.

Supasyndh O, Satirapoj B, Aramwit P, Viroonudomphol D, Chaiprasert A, Thanachatwej V · Clin J Am Soc Nephrol (2013)

The efficacy of oxymetholone in combination with erythropoietin on hematologic parameters and muscle mass in CAPD patients.

Aramwit P, Palapinyo S, Wiwatniwong S, Supasyndh O · Int J Clin Pharmacol Ther (2010)

Oxymetholone ameliorates insulin sensitivity in maintenance hemodialysis patients: a randomized controlled trial.

Aramwit P, Kobpipat N, Satirapoj B, Kopple JD, Supasyndh O · Clin Nephrol (2009)

Oxymetholone for the treatment of HIV-wasting: a double-blind, randomized, placebo-controlled phase III trial in eugonadal men and women.

Hengge UR, Stocks K, Faulkner S, Wiehler H, Lorenz C, Jentzen W · HIV Clin Trials (2003)

Androgens for the anaemia of chronic kidney disease in adults.

Einfach gesagt: We found limited evidence ... to indicate that oxymetholone can increase haemoglobin (Hb) (MD 1.90 g/dL) ... alanine aminotransferase (ALT) (MD 54.50 U/L) ... and aspartate aminotransferase (AST) (MD 47.33 U/L); and decrease high-density lipoprotein (HDL) (MD -15.66 mg/dL).

Yang Q, Abudou M, Xie XS, Wu T · The Cochrane database of systematic reviews (2014)

Treatment of inherited bone marrow failure syndromes beyond transplantation.

Einfach gesagt: Androgens are the main nontransplant therapy for bone marrow failure in dyskeratosis congenita and Fanconi anemia, reaching responses in up to 80% of cases. Danazol and oxymetholone are more commonly used, but virilization and liver toxicity are major adverse events.

Calado RT, Clé DV · Hematology. American Society of Hematology. Education Program (2017)

Spontaneous liver rupture in a patient with peliosis hepatis: a case report.

Einfach gesagt: Here, we present a young male patient with aplastic anemia, who had received long-term treatment with oxymetholone ... peliosis hepatis ... may cause fatal hepatic hemorrhage and liver failure ... massive intra-abdominal bleeding should also be considered.

Choi SK, Jin JS, Cho SG, Choi SJ, Kim CS, Choe YM, Lee KY · World journal of gastroenterology (2009)