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Mp2.0
Pfefferminze – Forschung
Zu wenige bewertete Studien
12 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Pfefferminze sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2025–2026 mit einer typischen Studiengröße von 105 Teilnehmenden.
Basierend auf 12 Studien · 1 Meta-Analyse · 5 RCTs · 1,165 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Nach Outcome
Cognitive function
Überwiegend Mechanismus / Beobachtung3 Studien
Pain & analgesia
Überwiegend Mechanismus / Beobachtung3 Studien
Recovery
Zu wenige bewertete Studien2 Studien
Women's health
Zu wenige bewertete Studien2 Studien
Inflammation
Zu wenige bewertete Studien1 Studie
Immune support
Zu wenige bewertete Studien1 Studie
Digestive health
Zu wenige bewertete Studien1 Studie
Wound & ulcer healing
Zu wenige bewertete Studien1 Studie
Aktives Forschungsgebiet
12 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2025
1RCTn=105 · medium study2025
Einfach gesagt: Conclusions The sublingual application of M. piperita or E. cardamomum extract ice cubes presents a simple, safe, and effective non-pharmacological adjunct for managing PONV in patients recovering from laparoscopic cholecystectomy.
Kamalvand N, Shamsizadeh M, Tapak L, Azizi A. · Explore (New York, N.Y.) (2025)
For the active groups, each ice cube was impregnated with six drops of 10 % essential oil extract.
Results While trends indicated a greater reduction in nausea severity, vomiting frequency, and antiemetic demand in the M. piperita group compared to the E. cardamomum group, the intergroup differences were not statistically significant (p > 0.05).
Secondary outcomes included the frequency of vomiting episodes and requests for antiemetic medication, recorded over a 4-hour postoperative period.
Jin K, Yan S, Xu L. · Frontiers in medicine (2026)
Continuous outcomes were pooled as Hedges' g standardized mean differences (SMDs) with 95% CIs using random-effects REML models.
For acute nausea severity (4 RCTs, n = 336), essential oil-based interventions were associated with reduced symptoms versus control (SMD = -0.49, 95% CI -0.76 to -0.22; I 2 = 35.42%).
For vomiting frequency (2 RCTs, n = 144), the pooled effect was not significant (SMD = -0.25, 95% CI -0.75 to 0.25; I 2 = 56.52%).
Einfach gesagt: Additionally, with increasing global temperatures and growing concerns about animal welfare, menthol's cooling, methane-reducing, and analgesic properties present promising opportunities for advancing sustainable livestock practices.
Bernard B, Joshi H, Fan P. · International journal of molecular sciences (2025)
This review comprehensively examines the existing literature to assess menthol's effects on animal growth performance, product quality, immune function, gastrointestinal microbial ecosystems, and metabolism across various livestock species.
Notably, menthol shows potential for improving feed efficiency, mitigating chronic inflammation and oxidative stress, inhibiting environmental and gastrointestinal pathogens, and enhancing calcium absorption.
However, optimal dosages, treatment durations, synergies with other phytogenic compounds, and regulatory mechanisms require further investigation.
Einfach gesagt: Conclusions The 2% peppermint lidocaine spray did not demonstrate significantly better immediate pain reduction compared to 2% viscous lidocaine, but did improve the global quality of life in patients with head and neck cancer with chemoradiation-induced mucositis.
Upalananda K, Prasartseree T, Promsen R, Sukamol W, Sakpunpanom P, Setakornnukul J, Suiwongsa B, Thephamongkhol K, Rongthong W, Chantharasamee J. · Journal of pain and symptom management (2026)
Objectives The use of 2% lidocaine oral viscous is constrained by its inconvenience of portability, coupled with difficulty swallowing in some cases, and its unpleasant taste.
This study aimed to compare the effects of 2% peppermint lidocaine spray with conventional 2% lidocaine oral viscous on the immediate pain reduction score at baseline and 5 minutes, feasibility, and quality of life in head and neck cancer patients with chemoradiation-induced mucositis.
Results A total of 60 patients, patients in the 2% peppermint lidocaine spray group had significantly better scores on the OMWQ-HN-12 items and found it more practical to use and with a better flavor compared to the 2% lidocaine viscous group.
Einfach gesagt: Therefore, more carefully designed studies are needed to confirm this hypothesis.
Nishi R, Sagiyama K, Fukumoto T, Amitani H, Asakawa A. · Complementary medicine research (2025)
The risk of bias was not found to be severe (high risk of bias rate: 35.7 ± 3.4%); our critical review elucidated the heterogeneity of the reviewed studies.
However, as most studies have noted, the impact of peppermint scent should be assessed from multiple perspectives, including psychological, physiological, neurological, and pharmacological factors.
Conclusion In summary, drawing a definitive conclusion at this stage is premature.
Einfach gesagt: Conclusion The combination of SNB and PEO provides effective postoperative analgesia, improves recovery quality, reduces intraoperative hemodynamic fluctuations, and promotes early rehabilitation.
Zhou Z, Tang H, Liu M, Ji Z, Yang M, Shen J, Zhang M. · Explore (New York, N.Y.) (2026)
The Ropivacaine Group (SNB & SNB+PEO) showed significantly lower NRS scores than the Saline Group (C & PEO) immediately after extubation (0.5 [0.0, 2.0] vs. 2.0 [0.0, 4.0], P = 0.013).
The Aromatherapy Group (PEO & SNB+PEO) had significantly lower scores than the Placebo Group (C & SNB) at 24 h postoperatively (1.0 [0.8, 2.0] vs. 2.5 [1.0, 4.0], P < 0.001).
Einfach gesagt: Overall, PEO demonstrates considerable potential as an antimicrobial and wound-healing agent; however, more standardized and clinically oriented studies are required.
Twenty studies met the inclusion criteria, the majority of which were preclinical, comprising in vitro (35%), in vivo (30%), and combined in vitro/in vivo (30%) models.
The formulations investigated ranged from creams and gels to nanoemulsions, lipid carriers, films, and nanofibers, with concentrations varying from 0.5% to 20%.
Incorporation into nanostructured systems was associated with improved stability, enhanced skin permeation, and superior antimicrobial performance, particularly when combined with nanoparticles, metals, other bioactive compounds, or, in specific cases, clinical antibiotics such as levofloxacin.
Einfach gesagt: This nursing intervention is recommended to prevent and minimize the PONV occurrence and is made of ginger and mint.
Pashaei S, Akyüz N, Ersoy YE. · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses (2025)
These findings suggest that both ginger and peppermint essential oils are effective in alleviating PONV symptoms, with each group showing significant improvement compared with the control group.
Rhodes 1 item score was 0.48 ± 0.51 in the ginger group, 1.11 ± 0.64 in the peppermint group, and 1.37 ± 0.49 in the control group (P < .001).
Conclusions Results support that ginger and mint might have a positive effect if used to improve postoperative recovery quality.