Wir verwenden standardmäßig essenzielle Cookies (Anmeldung, deine gespeicherten Ziele/Stacks). Mit deiner Erlaubnis aktivieren wir außerdem datenschutzfreundliche Analytik (Vercel Web Analytics, anonyme Ladezeit-Metriken) und Fehler-Replay-Diagnostik (Sentry — DOM-Snapshots nur, wenn ein Fehler auftritt), damit wir Bugs schneller beheben können. Mehr über Cookies erfahren

Snl3.0

Snail Mucin – Forschung

Überwiegend Mechanismus / Beobachtung

6 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu Snail Mucin sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus gemischt-qualitativen randomisierten Studien, veröffentlicht 2013–2024 mit einer typischen Studiengröße von 40 Teilnehmenden.

Basierend auf 6 Studien · 1 RCT · 65 Teilnehmende insgesamt

Konfidenz

Geringe Konfidenz

Nach Outcome

Wound & ulcer healing
Zu wenige bewertete Studien2 Studien
Inflammation
Zu wenige bewertete Studien1 Studie
Skin healthVerbesserte Hydratation und Glätte durch einen glykoprotein-/HA-reichen Film (kosmetisch, kein gesundheitlicher Endpunkt) · 4-12 weeks · Geringfügige Verringerung des Erscheinungsbildes feiner Linien in einer kleinen Split-Face-Studie (kosmetisch; die Evidenz ist dünn) · 8-12 weeks
Zu wenige bewertete Studien1 Studie

Aktives Forschungsgebiet

3 Studien in den letzten 5 Jahren

201320182024

1Übersicht2024

Einfach gesagt: We also emphasize the need for appropriate clinical trials into the stated benefits of snail mucin to ensure consumer safety and ethical extraction of mucin.

Singh N, Brown AN, Gold MH. · Journal of cosmetic dermatology (2024)

Investigations into the global market found estimates ranging from $457 million to $1.2 billion with upward projections in the upcoming decade.
Limitations include ethical habitats for collection, allergy investigation, and missing clinical studies.
Conclusions The findings presented here emphasize the expanding uses of snail mucin and its ingredients alongside a growing market cosmetic industry should consider.

Quelle ansehen

2RCTn=25 · very small study2013

Einfach gesagt: Periocular rhytides on the active ingredient side showed significant improvement after 12 weeks (P=.03) and improved texture to a greater degree than placebo at 8 and 12 weeks, as well as 2 weeks after discontinuing the product (14 weeks).

Fabi SG, Cohen JL, Peterson JD, Kiripolsky MG, Goldman MP. · J Drugs Dermatol (2013)

Double-blind, randomized, split-face design (n=25): an 8% SCA emulsion plus 40% SCA serum on one side vs placebo on the other for 12 weeks
Periocular wrinkles on the SCA side improved significantly versus placebo (P=.03), with greater texture improvement at 8 and 12 weeks
Well tolerated; benefit was limited to periocular/fine rhytides — subjects reported no significant difference in overall skin quality

3Tierstudie2021

Einfach gesagt: Our macroscopic results show that the SSF treatment significantly improved the speed and percentage of wound area closure.

Gugliandolo E, Macrì F, Fusco R, Siracusa R, D'Amico R, Cordaro M, Peritore AF, Impellizzeri D, Genovese T, Cuzzocrea S, Paola RD, Licata P, Crupi R. · Vet Sci (2021)

Full-thickness excisional wound model in mice treated topically with snail secretion filtrate for 14 days
SSF accelerated wound closure and improved healing markers (collagen deposition, COL3A1, α-SMA, VEGF)
SSF reduced inflammatory markers (MPO, IL-1β, IL-6, TNF-α) — a growth-factor-like, pro-remodeling mechanism, but preclinical animal data

Quelle ansehen

4Übersicht2020

Einfach gesagt: Further research studies are warranted to elucidate any biological or therapeutic mechanisms of action of these ingredients, which may translate into clinical practice.

Nguyen JK, Masub N, Jagdeo J. · J Cosmet Dermatol (2020)

Narrative review of Korean cosmeceutical bioactives including snail mucin, surveying lab, animal, and clinical studies
Reports snail mucin shows bioactivities with potential for skin rejuvenation, photoprotection, and wound healing
Explicitly concludes further research is warranted before clinical translation — the evidence base is still emerging

Quelle ansehen

5Open-Labeln=40 · small study2017

Einfach gesagt: The formulation studied included moisturizing, emollient, film-forming, and retinoid ingredients in addition to the mollusk egg extract to produce the clinical improvement.

Draelos ZD. · J Drugs Dermatol (2017)

Single-arm, 12-week open-label study (n=40, ages 40-70) of a mollusk-egg anti-aging cream twice daily
Investigator ratings improved at week 12: 53% less roughness (P<0.001), 26% more brightness (P<0.001), 39% higher elasticity (P<0.001)
Confounded: the formulation also contained emollient, film-forming, and retinoid ingredients, with no placebo control — the effect can't be attributed to the snail extract

6In vitro2024

Einfach gesagt: HASC extract exhibited superior inhibitory activity compared to HAS against collagenase and tyrosinase enzymes (IC50 = 8.4 ± 1.19 vs. 15.3 ± 1.12 μg/mL) and (IC50 = 30.1 ± 0.91 vs. 35 ± 1.3 μg/mL).

Alkhadhrh M, Issa R, Al-Halaseh LK, Alnsour L, Alsarayreh A, Al Qaisi Y, Matalqah SM, Aladwan S. · J Cosmet Dermatol (2024)

In-vitro characterization of Helix aspersa snail slime; identified phenolics, flavonoids, ascorbic acid, and fatty acids
Slime extracts showed antioxidant activity and dose-dependent inhibition of collagenase and tyrosinase — the enzymatic basis for anti-aging/brightening claims
Purely biochemical assays; no skin, cell, animal, or human outcomes — speaks only to plausible mechanism

Quelle ansehen

In der Forschungsbibliothek ansehen

Snail Mucin – Forschung

Überwiegend Mechanismus / Beobachtung

Snail extract for skin: A review of uses, projections, and limitations

The Effects of Filtrate of the Secretion of the Cryptomphalus Aspersa on Photoaged Skin.

The Protective Effect of Snail Secretion Filtrate in an Experimental Model of Excisional Wounds in Mice.

Bioactive ingredients in Korean cosmeceuticals: Trends and research evidence.

The Role of a Natural Mollusk Egg-Derived Ingredient in Facial Appearance.

Investigating the inhibitory effects of carotenoids-fortified Helix aspersa slime on oxidative stress, collagenase and tyrosinase enzyme activities.