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SPM6.2
Spearmint – Forschung
Überwiegend Mechanismus / Beobachtung
15 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Spearmint sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen randomisierten Studien, veröffentlicht 2007–2024 mit einer typischen Studiengröße von 24 Teilnehmenden.
Basierend auf 15 Studien · 8 RCTs · 135 Teilnehmende insgesamt
Konfidenz
Mittlere Konfidenz
Nach Outcome
Cognitive functionVerbessertes Arbeitsgedächtnis und räumliches Gedächtnis bei Erwachsenen mit altersbedingter Gedächtnisbeeinträchtigung · 4–12 Wochen
Überwiegend Mechanismus / Beobachtung6 Studien
PCOS, hirsutism & hormonalSignifikante Reduktion des freien Testosteronspiegels; Verbesserung des LH/FSH-Verhältnisses · 4–8 Wochen · Reduktion androgenbedingter Symptome; mögliche Stimmungs- und Hormonstabilisierung · 4–8 Wochen
Überwiegend Mechanismus / Beobachtung3 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung3 Studien
Safety profile
Überwiegend Mechanismus / Beobachtung3 Studien
InflammationVerringerte Gelenkschmerzen und Steifigkeit bei Kniearthrose · 8–16 Wochen
Zu wenige bewertete Studien2 Studien
Men's vitalityVerringerte Androgenspiegel und verbessertes Gonadotropin-Profil bei Frauen mit PCOS · 4–8 Wochen
Zu wenige bewertete Studien2 Studien
Joint pain & arthritisVerringerte Knieschmerzen und Steifigkeit bei Arthrose-Patienten · 8–16 Wochen
Zu wenige bewertete Studien1 Studie
Stetige Forschung
3 Studien in den letzten 5 Jahren
200720152024
1Systematische Übersicht2010
Ulbricht C, Costa D, M Grimes Serrano J, Guilford J, Isaac R, Seamon E · J Diet Suppl (2010)
Einfach gesagt: Supplementation with spearmint extract significantly improved working memory in men and women with age-associated memory impairment compared to placebo.
Herrlinger KA et al. · Journal of alternative and complementary medicine (New York, N.Y.) (2018)
Adults with age-associated memory impairment receiving 900 mg/day spearmint extract showed significant improvements in spatial working memory.
The 90-day RCT demonstrated benefits in both sexes, suggesting broad cognitive applicability.
Rosmarinic acid was identified as a key bioactive compound mediating neuroprotective effects.
Einfach gesagt: This review will, therefore, contribute to the rational and economic exploration of spearmint aromatic molecules as natural and safe alternative therapeutics.
Zhang LL et al. · Food & function (2022)
Besides their traditional use, these aromatic molecules have attracted great interest in other application fields (e.g., medicine, agriculture, food, and beverages) especially due to their antimicrobial, antioxidant, insecticidal, antitumor, anti-inflammatory and antidiabetic activities.
This review presents the sources, properties, synthesis and application of spearmint aromatic molecules.
Furthermore, this review focuses on the biological properties so far described for these compounds, their therapeutic effect on some diseases, and future directions of research.
Einfach gesagt: Results indicate that Indian pennywort, Sea buckthorn, Spearmint oil and ginger are beneficial in mitigating RINV.
Palatty PL et al. · International journal of radiation biology (2024)
Results indicate that Indian pennywort, Sea buckthorn, Spearmint oil and ginger are beneficial in mitigating RINV.
Also, of the four plants investigated in preclinical models of study, mint oil and ginger seem to be more useful and merit structured systematic translational studies to ascertain the benefit of these two agents.
Einfach gesagt: Peppermint (Mentha piperita) essential oil with high levels of menthol/menthone and characteristic in vitro cholinergic inhibitory, calcium regulatory and GABAA/nicotinic receptor binding properties, beneficially modulated performance on demanding cognitive tasks and attenuated the increase in mental fatigue associated with extended cognitive task performance in healthy adults.
Kennedy D et al. · Nutrients (2018)
Spearmint and peppermint (Mentha spicata/piperita) essential oils were pre-screened for neurotransmitter receptor binding and acetylcholinesterase (AChE) inhibition; peppermint had the most promising in vitro profile and was selected for the human trial.
In a double-blind, placebo-controlled crossover study, 24 participants consumed single oral doses of the peppermint essential oil.
The 100 µL dose improved performance on the Rapid Visual Information Processing task and attenuated mental fatigue on a demanding subtraction task.
13Nausea and vomiting symptomsSystematische Übersicht2020
Einfach gesagt: Herbal medicines such as matricaria chamomilla, elettaria cardamomum, pomegranate and spearmint syrup, lemon provide safe and effective medical alternatives for treating pregnant women with mild to moderate nausea and vomiting of pregnancy.
Khorasani F et al. · Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2020)
Spearmint syrup was identified as one of several herbal alternatives showing efficacy for mild-to-moderate pregnancy nausea and vomiting.
Ginger demonstrated the strongest evidence across all reviewed herbal interventions for nausea and vomiting of pregnancy.
Mentha preparations showed variable results, with some positive effects on nausea but not consistently on vomiting.
Einfach gesagt: After treatment with spearmint teas, there was a significant decrease in free testosterone and increase in luteinizing hormone, follicle-stimulating hormone and estradiol.
Akdoğan M et al. · Phytotherapy research : PTR (2007)
Twenty-one hirsute women (12 PCOS, 9 idiopathic) consumed spearmint tea twice daily for 5 days in the follicular phase.
15Herbal medicine use patterns and safetySystematische Übersicht2014
Einfach gesagt: Spearmint and other mint-family herbs are among the most commonly used herbal medicines by elderly patients, with a generally favorable safety profile but potential for interactions with conventional medications.
de Souza Silva JE et al. · Archives of gerontology and geriatrics (2014)
Spearmint was identified as one of the most frequently consumed herbal medicines in elderly populations globally.
The review highlighted the importance of considering herb-drug interactions in elderly patients on polypharmacy regimens.
Overall safety of mint family herbs was found to be acceptable, with most adverse effects being mild and transient.