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Tm4.0
Tremella – Forschung
Überwiegend Mechanismus / Beobachtung
15 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Tremella sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen randomisierten Studien, veröffentlicht 2012–2026 mit einer typischen Studiengröße von 60 Teilnehmenden.
Basierend auf 15 Studien · 2 RCTs · 176 Teilnehmende insgesamt
Konfidenz
Geringe Konfidenz
Was die Studien gefunden haben
1geholfen· 14 weitere ohne bewertete Effektdaten
Nach Outcome
Skin healthPolysaccharide können bei der Hautfeuchtigkeit mit Hyaluronsäure konkurrieren · 4-8 Wochen
1Neuroprotection from medicinal mushroomsÜbersicht2026
Einfach gesagt: This review explores for the first time the complex interplay between infections and neurological disorders, highlighting the potential of mushrooms not only as functional foods but also as complem...
Buttacavoli M et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2026)
This review explores for the first time the complex interplay between infections and neurological disorders, highlighting the potential of mushrooms not only as functional foods but also as complementary allies in safeguarding brain health.
Einfach gesagt: Additionally, it provides a theoretical basis for the potential applications of TFP in the food, pharmaceutical, and cosmetic industries, while also discussing future research directions and development prospects.
Rui Y et al. · Journal of food science (2025)
Extensive studies have demonstrated that TFP exhibits significant bioactivities, including antioxidant, antitumor, immunomodulatory, memory-enhancing, anti-inflammatory, hypoglycemic, and hypolipidemic effects, as well as skin-protective properties and gut microbiota modulation.
Due to these multifunctional properties, TFP has garnered considerable attention in the food, pharmaceutical, and cosmetic industries.
This review summarizes recent research on TFP, focusing on its preparation methods, structural characteristics, and diverse biological activities.
3Anti-aging effects of macrofungal extracts on skinÜbersicht2024
Einfach gesagt: According to available literature data, macrofungi contain many polysaccharides, phenolic compounds, polysaccharide peptides, free amino acids, sterols, proteins, glycosides, triterpenes, alkaloids, which can have an anti-aging effect on the skin by acting as antioxidants, photoprotective, skin whitening, moisturizing, anti-inflammatory and stabilizing collagen, elastin and hyaluronic acid levels in the skin.
Paterska M et al. · Nutrients (2024)
To slow down this process, natural anti-aging skincare ingredients are being sought.
In this review, 52 scientific publications about the effects of chemical compounds extracted from the fruiting bodies of macrofungi on skin cells were selected.
The effects of extracts from nine species that are tested for anti-aging effects have been described.
4Tremella polysaccharide production and applicationsÜbersicht2021
Einfach gesagt: The application prospect of Tremella polysaccharide in against multiple sub-health states was worth expecting.
Ma X et al. · International journal of immunopathology and pharmacology (2021)
Tremella polysaccharide is known to be structurally unique and biologically active natural products, abundant and versatile in activities and applications in food industry, daily chemical industry and medicine industry.
In order to improve the industrialisation of Tremella polysaccharide, the limitations of preparation and structure-activity relationship of Tremella polysaccharide were reviewed in this paper.
The research progress of Tremella polysaccharide in the past 20 years was summarized from the sources, preparation methods, molecular structure, activity and application, and the research trend in the future was also prospected.
5Bioactivities of Tremella fuciformis polysaccharidesÜbersicht2019
Einfach gesagt: In the past decades, many researchers have reported that T. fuciformis polysaccharides (TPS) possess various bioactivities, including anti-tumor, immunomodulatory, anti-oxidation, anti-aging, repai...
Wu YJ et al. · International journal of biological macromolecules (2019)
In the past decades, many researchers have reported that T. fuciformis polysaccharides (TPS) possess various bioactivities, including anti-tumor, immunomodulatory, anti-oxidation, anti-aging, repairing brain memory impairment, anti-inflammatory, hypoglycemic and hypocholesterolemic.
The structural characteristic of TPS has also been extensively investigated using advanced modern analytical technologies such as NMR, GC-MS, LC-MS and FT-IR to dissect the structure-activity relationship (SAR) of the TPS biomacromolecule.
This article reviews the recent progress in the extraction, purification, structural characterization and applications of TPS.
6Tremella polysaccharide drug action mechanismsÜbersicht2019
Einfach gesagt: In this chapter, 113 independent studies involving in biochemical, pharmacological, and clinical studies of TFPS during the past 46 years (1972-2018) on the base of PubMed, CNKI (China National Kno...
Yang D et al. · Progress in molecular biology and translational science (2019)
In this chapter, 113 independent studies involving in biochemical, pharmacological, and clinical studies of TFPS during the past 46 years (1972-2018) on the base of PubMed, CNKI (China National Knowledge Infrastructure) and Wanfang database search are summarized.
TFPS shows efficacy for all types of human diseases in the reported clinical studies.
The structure, molecular mechanisms of the immunomodulation, antitumor, anti-oxidation, anti-aging, hypoglycemic, hypolipidemic, preclinical and clinical efficacy are discussed to provide a general picture of TFPS as a clinically used drug.
Einfach gesagt: This formula beverage is a promising option that could be used to prevent further cognitive decline in adults with subjective cognitive complaints.
Lin YK et al. · Nutrients (2023)
After 4 and 8 weeks, there was a significant increase in the number of memory cards, and the response times among those who consumed the formula beverage were significantly faster than those in the placebo group.
There was a significant increase in the cue effect of happy facial expressions after the subjects consumed the formula beverage for 8 weeks.
In addition, there was a significant decrease in anxiety and fatigue, and improved quality of life.
11Bioactive effects of Tremella fuciformis polysaccharidesÜbersicht2025
Einfach gesagt: The findings suggest that TFPs are promising natural bioactive compounds with potential applications in disease prevention and treatment, and they represent valuable candidates for the development of functional foods and therapeutic agents.
Li S, Zhao K, Li J, Li X, Zhao H, Cui R, Li J, Guo J, Bian X. · Frontiers in nutrition (2025)
Its main bioactive constituents, Tremella fuciformis polysaccharides (TFPs), have attracted considerable attention in both food and pharmaceutical industries due to their diverse biological activities.
TFPs exhibit a broad spectrum of health-promoting effects, including microbial homeostasis, immuno-modulatory, antioxidant, anti-hyperglycemic, anti-hyperlipidemia, and others.
This review summarizes recent advances in the extraction, purification, structural characterization, and pharmacological action of TFPs.
Einfach gesagt: This review is intended to provide a theoretical basis for the further investigation and application of TFPs in cosmetics, functional foods, beverages, and healthcare products.
Luan F et al. · International journal of biological macromolecules (2026)
In this review, we provide a comprehensive overview of the extraction, purification, structural characteristics, pharmacological properties, and underlying mechanisms of TFPs.
In addition, the structure-activity relationships, potential applications, safety evaluation, and modification strategies associated with their bioactivities are highlighted, together with a discussion of future research directions.
This review is intended to provide a theoretical basis for the further investigation and application of TFPs in cosmetics, functional foods, beverages, and healthcare products.
Einfach gesagt: Tremella fuciformis polysaccharides have great prospects but lack clarity on some mechanisms, higher-order structure research, and standardized quality criteria.
Liao Y et al. · Carbohydrate research (2026)
Sehr groß Nutzen
← SchlechterKein EffektBesser →
Tremella fuciformis polysaccharides have diverse extraction methods (hot water, ultrasonic/microwave-assisted, etc.), with composite tech boosting yield over 50%.
Tremella fuciformis polysaccharides have great prospects but lack clarity on some mechanisms, higher-order structure research, and standardized quality criteria.
With deeper study, they may bring new breakthroughs in industries of health maintenance, disease treatment, and cosmetics and skincare.
15Immunomodulatory and anticancer activitiesIn vitro2015
Einfach gesagt: Taken together, our results indicated that T1 and T6 strains of TFs showed the similar immune modulatory and anticancer abilities were better than the CH strain of TFs.
Han CK et al. · The American journal of Chinese medicine (2015)
On the other hand, the cold water extracts of TFs, especially of T1C, obviously suppressed cancer cell survival better than those of hot water extracts.
Interestingly, we found that hot water extracts of TFs may augment necrotic cell death, whereas, cold water extracts of TFs induce apoptosis.
Furthermore, we also showed that these TFs activate caspase-3 cleavage, up regulate the Bax/Bcl-2 ratio, and decrease MMP-9 expressions in PC-3 cells.