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Studien
Vc8.0
Vitamin C – Forschung
Hilft vermutlich
984 begutachtete Studien
Was die Evidenz sagt
Hilft vermutlich
Vitamin C half in etwa der Hälfte (6/10) der Studien, die einen Effekt gemessen haben — vielversprechend, aber nicht einhellig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1997–2026 mit einer typischen Studiengröße von 214 Teilnehmenden.
Basierend auf 981 Studien · 152 Meta-Analysen · 769 RCTs · 65,572 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
6geholfen3unklar1nicht geholfen· 971 weitere ohne bewertete Effektdaten
Einfach gesagt: While evidence from short-term studies suggests that vitamin C supplementation may improve glycemic control and BP in people with type 2 diabetes, vitamin C supplementation cannot currently be recommended as a therapy until larger, long-term, and high-quality trials confirm these findings.
Mason SA et al. · Diabetes care (2021)
While evidence from short-term studies suggests that vitamin C supplementation may improve glycemic control and BP in people with type 2 diabetes, vitamin C supplementation cannot currently be recommended as a therapy until larger, long-term, and high-quality trials confirm these findings.
3In-hospital mortalityMeta-Analysen=1,800 · large study2022
Einfach gesagt: The use of vitamin C reduces hospital mortality. The length of stay in the ICU is longer among patients treated with vitamin C.
Olczak-Pruc M et al. · Nutrients (2022)
Groß Nutzen
← SchlechterKein EffektBesser →
Likely real
In-hospital mortality with and without vitamin C supplementation was 24.1% vs. 33.9% (OR = 0.59; 95%CI: 0.37 to 0.95; p = 0.03), respectively.
The ICU length of stay was longer in patients treated with vitamin C vs. standard therapy, 11.1 (7.3) vs. 8.3 (4.7) days (MD = 1.91; 95%CI: 0.89 to 2.93; p < 0.001), respectively.
Despite some evidence of the usefulness of vitamin C in modifying the course of COVID-19, it is too early to modify guidelines and recommendations.
4Term PROM with vitamin C and E supplementationMeta-Analysen=20,038 · very large study2015
Einfach gesagt: The data do not support routine vitamin C supplementation alone or in combination with other supplements for the prevention of fetal or neonatal death, poor fetal growth, preterm birth or pre-eclampsia.
Rumbold A et al. · The Cochrane database of systematic reviews (2015)
Sehr groß Schaden
← SchlechterKein EffektBesser →
Conversely, the risk of term PROM was increased when supplementation included vitamin C and vitamin E (average RR 1.73, 95% CI 1.34 to 2.23; 3060 participants; two studies; I² = 0%).
The data do not support routine vitamin C supplementation alone or in combination with other supplements for the prevention of fetal or neonatal death, poor fetal growth, preterm birth or pre-eclampsia.
Further research is required to elucidate the possible role of vitamin C in the prevention of placental abruption and prelabour rupture of membranes.
6Mortality due to pneumoniaSystematische Übersichtn=2,774 · very large study2021
Einfach gesagt: We are uncertain of the effect of vitamin C supplementation for the prevention and treatment of pneumonia due to very low-certainty evidence.
Padhani ZA et al. · The Cochrane database of systematic reviews (2021)
Kein klarer Effekt
← SchlechterKein EffektBesser →
Included 5 studies with 2655 participants (2 RCTs, 3 quasi-RCTs)
2 studies assessed vitamin C for pneumonia prevention; 3 assessed it for treatment
Evidence rated very low certainty; effect on pneumonia prevention and treatment uncertain