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White Kidney Bean Extract – Forschung

Überwiegend Mechanismus / Beobachtung

5 begutachtete Studien

Was die Evidenz sagt

Überwiegend Mechanismus / Beobachtung

Die meisten Studien zu White Kidney Bean Extract sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.

Die meiste Evidenz stammt aus mittelwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 2007–2026 mit einer typischen Studiengröße von 81 Teilnehmenden.

Basierend auf 5 Studien · 2 Meta-Analysen · 2 RCTs · 684 Teilnehmende insgesamt

Konfidenz

Hohe Konfidenz

Nach Outcome

Weight managementInkonsistent; eine Meta-Analyse fand keinen signifikanten Gewichtsverlust gegenüber Placebo, obwohl einige kleine Studien moderate Fett-/Gewichtsreduktionen berichten · 4-12 Wochen (falls überhaupt)
Überwiegend Mechanismus / Beobachtung5 Studien
Safety profile
Zu wenige bewertete Studien2 Studien
Glucose & metabolicPlausible Abschwächung postprandialer Glukosespitzen durch Verlangsamung der Stärkeverdauung, jedoch sind humane Daten zu glykämischen Endpunkten begrenzt · Pro Mahlzeit (akut)
Zu wenige bewertete Studien1 Studie

Aktives Forschungsgebiet

2 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2026

200720162026

1Meta-Analysen=543 · large study2026

In the future, further large-scale, high-quality, and long-term trials are warranted to confirm its efficacy and clarify its potential role in metabolic health.

Shi N, Wang R, Cao X, Huang Z, Lin F, Xu R, Zhang Q. · Nutrition research (New York, N.Y.) (2026)

We hypothesized that WKBE could significantly improve key anthropometric outcomes in adults with overweight and obese compared with placebo, with acceptable safety.
No significant differences were observed in fasting blood glucose, triglycerides, or random insulin.
No serious adverse events related to WKBE were reported.

Quelle ansehen

2Beobachtungsstudien=81 · small study2024

ClinicalTrials.gov identifier NCT02930668.

Jäger R, Abou Sawan S, Purpura M, Grube B, Röske Y, De Costa P, Chong PW. · Scientific reports (2024)

In a dose-dependent manner, Phase 2 significantly reduced body weight, fat mass, BMI, waist, hip and in the WKBE HIGH group thigh circumference.
Phase 2 is an effective and safe supplement aiding weight and fat loss.
ClinicalTrials.gov identifier NCT02930668.

Quelle ansehen

3Meta-Analyse2011

The poor quality of the included RCT prevents us from drawing any firm conclusions about the effects of P. vulgaris supplementation on body weight.

Onakpoya I, Aldaas S, Terry R, Ernst E. · Br J Nutr (2011)

Of 11 eligible trials, 6 were included; all had serious methodological flaws
Pooled weight loss was NOT statistically significant versus placebo (MD -1.77 kg, 95% CI -3.33 to 0.33)
A significant body-fat reduction was found (MD -1.86 kg) but with heterogeneity between trials

Quelle ansehen

4RCT2014

At the end of the WL study, the IQP-PV-101 group lost a mean of 2.91 ± 2.63 kg in body weight compared with 0.92 ± 2.00 kg in the placebo group (P < 0.001).

Grube B, Chong WF, Chong PW, Riede L. · Obesity (Silver Spring) (2014)

Double-blind 12-week weight-loss phase plus 24-week open-label maintenance, all on a mildly hypocaloric diet
The extract group lost ~2.91 kg vs ~0.92 kg for placebo (a roughly 2 kg net difference)
No serious or related adverse events over 36 weeks

Quelle ansehen

5RCTn=60 · small study2007

After 30 days, subjects receiving Phaseolus vulgaris extract with a carbohydrate-rich, 2000- to 2200-calorie diet had significantly (p<0.001) greater reduction of body weight, BMI, fat mass, adipose tissue thickness, and waist,/hip/ thigh circumferences while maintaining lean body mass compared to subjects receiving placebo.

Celleno L, Tolaini MV, D'Amore A, Perricone NV, Preuss HG. · Int J Med Sci (2007)

Small randomized double-blind placebo-controlled trial (n=60) over just 30 days
Reported significant reductions in body weight, BMI, fat mass, and waist/hip/thigh circumference vs placebo
Very short duration and small sample; author list includes supplement-industry-affiliated names (industry-linked)

Quelle ansehen

In der Forschungsbibliothek ansehen

White Kidney Bean Extract – Forschung

Überwiegend Mechanismus / Beobachtung

White kidney bean extract reduces body weight and adiposity with acceptable safety in adults with overweight and obese: a systematic review and meta-analysis

Proprietary alpha-amylase inhibitor formulation from white kidney bean (Phaseolus vulgaris L.) promotes weight and fat loss: a 12-week, double-blind, placebo-controlled, randomized trial

The efficacy of Phaseolus vulgaris as a weight-loss supplement: a systematic review and meta-analysis of randomised clinical trials.

Weight reduction and maintenance with IQP-PV-101: a 12-week randomized controlled study with a 24-week open label period.

A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women.