We use essential cookies (authentication, your saved goals/stack) by default. With your permission we'll also enable privacy-respecting analytics (Vercel Web Analytics, anonymous load-time metrics) and error-replay diagnostics (Sentry — DOM snapshots only when an error fires) so we can fix bugs faster. Learn more about cookies

Aci2.5

Acai Research

Mostly mechanism / observationalHigh safety

4 peer-reviewed studies

What the evidence says

Mostly mechanism / observational

Most Acai studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.

Most evidence is from medium-quality randomised trials published 2008–2020 with a typical study size of 30 participants.

Based on 4 studies · 3 RCTs · 100 total participants

Confidence

Moderate

By outcome

Glucose & metabolicSmall short-term trials show modest HDL and antioxidant-enzyme shifts; no effect on glucose or lipid metabolism in metabolic-syndrome patients · 4-12 weeks (biomarker level only)
Too few graded studies1 study

Older research base

Newest study from 2020

200820142020

1RCTn=37 · small study2018

Only two of many inflammation/oxidative-stress biomarkers improved over 12 weeks, with no change in glucose or lipid metabolism — the authors call this 'a weak indication' requiring higher doses before any conclusions.

Kim H, Simbo SY, Fang C, McAlister L, Roque A, Banerjee N, Talcott ST, Zhao H, Kreider RB, Mertens-Talcott SU · Food Funct (2018)

Randomized, double-blind, placebo-controlled pilot in 37 metabolic-syndrome patients over 12 weeks
Plasma IFN-γ and urinary 8-isoprostane decreased significantly vs placebo
NO significant change in any lipid- or glucose-metabolism biomarker

View source

2Crossovern=30 · small study2020

Açaí juice raised HDL-c by ~8% and increased antioxidant-enzyme activity vs baseline, but there were no significant between-group differences.

de Liz S, Cardoso AL, Copetti CLK, Hinnig PF, Vieira FGK, da Silva EL, Schulz M, Fett R, Micke GA, Di Pietro PF · Clin Nutr (2020)

Randomized crossover in 30 healthy adults, 200 mL/day for 4 weeks
HDL-c rose 7.7% and antioxidant enzymes (catalase, GPx) increased vs baseline
No significant intergroup differences for any outcome (P > 0.05)

View source

3Crossovern=12 · very small study2008

Acai anthocyanins were absorbed and transiently increased plasma antioxidant capacity in an acute crossover trial.

Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, Pacheco-Palencia LA, Meibohm B, Talcott ST, Derendorf H · J Agric Food Chem (2008)

Acute four-way crossover in 12 healthy volunteers
Confirmed absorption of acai anthocyanins with peak plasma levels ~2 h
Plasma antioxidant capacity transiently increased up to 2.3-3 fold

View source

4Open-Labeln=21 · very small study2018

The study did not meet its primary endpoint of 50% PSA response; only 1 of 21 patients had a PSA response.

Kessler ER, Su LJ, Gao D, Torkko KC, Wacker M, Anduha M, Chronister N, Maroni P, Crawford ED, Flaig TW, Glode LM, Lam ET · Integr Cancer Ther (2018)

Phase II single-arm trial in 21 men with biochemically recurrent prostate cancer
Did NOT meet its primary endpoint (50% PSA response) — only 1 responder
PSA doubling time lengthened in 71% of patients (secondary, uncontrolled observation)

View source

View in Research Library

Acai Research

Mostly mechanism / observational

Açaí (Euterpe oleracea Mart.) beverage consumption improves biomarkers for inflammation but not glucose- or lipid-metabolism in individuals with metabolic syndrome in a randomized, double-blinded, placebo-controlled clinical trial.

Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study.

Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers.

Phase II Trial of Acai Juice Product in Biochemically Recurrent Prostate Cancer.