Skov K, Graudal NA, Jürgens G · Basic Clin Pharmacol Toxicol (2021)
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143 peer-reviewed studies
What the evidence says
Most Activated Charcoal studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1974–2026 with a typical study size of 348 participants.
Based on 143 studies · 2 meta-analyses · 137 RCTs · 944 total participants
Confidence
High confidenceBy outcome
Only 9 studies in the last 5 years · Latest meta-analysis: 2021
Skov K, Graudal NA, Jürgens G · Basic Clin Pharmacol Toxicol (2021)
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Jürgens G, Hoegberg LC, Graudal NA · Clin Pharmacol Ther (2009)
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Roberts DM, Buckley NA · Cochrane Database Syst Rev (2006)
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Canitrot E, Turgeon AF, Moore L, Diendéré E, St-Onge M · J Med Toxicol (2023)
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Hoegberg LCG, Shepherd G, Wood DM, Johnson J, Hoffman RS, Caravati EM · Clin Toxicol (Phila) (2021)
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Chamberlain JM, Gorman RL, Oderda GM, Klein-Schwartz W, Klein BL · Ann Emerg Med (1993)
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Mayer AL, Sitar DS, Tenenbein M · Arch Intern Med (1992)
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Galinsky RE, Levy G · J Toxicol Clin Toxicol (1984)
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Ollier E, Hodin S, Lanoiselée J, Escal J, Accassat S, De Magalhaes E · Clin Pharmacokinet (2017)
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Park GD, Goldberg MJ, Spector R, Johnson GF, Feldman RD, Quee CK · Drug Intell Clin Pharm (1985)
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Park GD, Spector R, Kitt TM · J Clin Pharmacol (1988)
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Neuvonen PJ, Elonen E · Br Med J (1980)
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Lapatto-Reiniluoto O, Kivistö KT, Neuvonen PJ · Clin Pharmacol Ther (2001)
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Neuvonen PJ, Kuusisto P, Vapaatalo H, Manninen V · Eur J Clin Pharmacol (1989)
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el-Bahie N, Allen EM, Williams J, Routledge PA · Br J Clin Pharmacol (1985)
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Olkkola KT, Neuvonen PJ · J Toxicol Clin Exp (1989)
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Neuvonen PJ, Elonen E, Mattila MJ · Clin Pharmacol Ther (1980)
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Scholtz EC, Jaffe JM, Colaizzi JL · Am J Hosp Pharm (1978)
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Goldberg MJ, Park GD, Spector R, Fischer LJ, Feldman RD · Clin Pharmacol Ther (1985)
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Zanganeh M, Abbasi A, Khosravi A, Amerian M, Ebrahimi H · Saudi J Kidney Dis Transpl (2023)
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