1Meta-Analysis2017
Lee HW, Lim HJ, Jun JH, Choi J, Lee MS · Curr Vasc Pharmacol (2017)
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48 peer-reviewed studies
What the evidence says
Most American Ginseng studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1991–2026 with a typical study size of 952 participants.
Based on 48 studies · 2 meta-analyses · 36 RCTs · 952 total participants
Confidence
High confidenceBy outcome
3 more outcomes with fewer studies not shown.
9 studies in the last 5 years · Latest meta-analysis: 2017
Lee HW, Lim HJ, Jun JH, Choi J, Lee MS · Curr Vasc Pharmacol (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Arring NM, Millstine D, Marks LA, Nail LM · J Altern Complement Med (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: Such effects suggest that P. quinquefolius extract may have benefits to everyday cognitive function.
Bell L, Fança-Berthon P, Cozannet RL, Ferguson D, Scholey A, Williams C. · Nutritional neuroscience (2026)
Sadeghian M, Rahmani S, Zendehdel M, Hosseini SA, Zare Javid A · Nutr Cancer (2021)
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Mucalo I, Jovanovski E, Rahelić D, Božikov V, Romić Z, Vuksan V · J Ethnopharmacol (2013)
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Best T, Clarke C, Nuzum N, Teo WP · Nutr Neurosci (2021)
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Vuksan V, Stavro MP, Sievenpiper JL, Beljan-Zdravkovic U, Leiter LA, Josse RG · Diabetes Care (2000)
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Dickman JR, Koenig RT, Ji LL · J Am Coll Nutr (2009)
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Kim E, Cameron M, Lovera J, Schaben L, Bourdette D, Whitham R · Mult Scler (2011)
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Guglielmo M, Di Pede P, Alfieri S, Bergamini C, Platini F, Ripamonti CI · J Cancer Res Clin Oncol (2020)
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Stavro PM, Woo M, Leiter LA, Heim TF, Sievenpiper JL, Vuksan V · Hypertension (2006)
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Barton DL, Liu H, Dakhil SR, Linquist B, Sloan JA, Nichols CR · J Natl Cancer Inst (2013)
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Hsu CC, Ho MC, Lin LC, Su B, Hsu MC · World J Gastroenterol (2005)
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Predy GN, Goel V, Lovlin R, Donner A, Stitt L, Basu TK · CMAJ (2005)
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Bell L, Whyte A, Duysburgh C, Marzorati M, Van den Abbeele P, Le Cozannet R · Eur J Nutr (2022)
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Lin CH, Lin YA, Chen SL, Hsu MC, Hsu CC · Nutrients (2021)
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Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V · J Am Coll Nutr (2004)
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Yuan CS, Wei G, Dey L, Karrison T, Nahlik L, Maleckar S · Ann Intern Med (2004)
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Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V · Eur J Clin Nutr (2003)
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White DJ, Camfield DA, Ossoukhova A, Savage K, Le Cozannet R, Fança-Berthon P · Hum Psychopharmacol (2020)
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