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Astragalus membranaceus (Huang Qi)
Contains cycloastragenol for potential telomere lengthening and polysaccharides for immune resilience — a cornerstone of Chinese longevity medicine.
What the evidence says
Astragalus helped in about half (2/4) of the studies that measured an effect — promising, but not unanimous.
Most evidence is from high-quality meta-analyses and randomised trials published 2003–2026 with a typical study size of 1,443 participants.
Based on 42 studies · 16 meta-analyses · 4 RCTs · 39,616 total participants
Confidence
HighWhat the studies found
By outcome
Astragalus has an evidence score of 7/10 — strong evidence based on 42 indexed studies, including 20 meta-analyses. Contains cycloastragenol for potential telomere lengthening and polysaccharides for immune resilience — a cornerstone of Chinese longevity medicine.
The commonly studied dose of Astragalus is 500-1500mg extract. Research points to an estimated optimal dose around 1500mg, with a minimum effective dose near 500mg. Individual response varies — start low and adjust.
The best time to take Astragalus is in the morning. Taking it with food is preferred. Astragalus polysaccharides and saponins (astragalosides) support immune function and may have mild energizing adaptogenic properties.
Spirulina
Likely helpsBlue-green algae with 60-70% complete protein and unique phycocyanin antioxidant — lowers cholesterol, blood pressure, and blood sugar.
Aged Garlic Extract
Likely helpsOdorless garlic extract with strong evidence for cardiovascular health, blood pressure, and immune support.
Last reviewed May 2026 · evidence from 39 studies · how we score
This information is for educational purposes only. It is not a substitute for professional medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication.
Astragalus is one of the most important herbs in Traditional Chinese Medicine, used for thousands of years to support immune function and vitality. Modern research has focused on its polysaccharides for immune support and cycloastragenol for potential telomere-lengthening effects. Used for immune resilience and healthy aging.
Enhances immune cell activity
May support telomere maintenance
How Astragalus works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
500-1500mg extract
Take with food
| Form | Type |
|---|---|
| 💊Standardized root extract | Recommended |
| 🧪Root powder | Alternative |
| 🍵Tea | Alternative |
| 💧Tincture | Alternative |
Look for extracts standardized to polysaccharides or astragalosides.
Minimum: 4 weeks
Optimal: 12 weeks
Cycling: Not required
Note: Can be taken any time of day. Traditional use often involves daily consumption.
Based on multiple meta-analyses showing adjuvant benefits for diabetic conditions. Effects appear time-dependent (>12 weeks). Studies primarily used combination therapy rather than astragalus alone.
Enhanced immune resilience
Improved overall vitality
Traditionally used but limited safety data; consult doctor
May counteract immunosuppressive effects
May affect lithium excretion
Possible reduced effectiveness
Possible organ rejection risk
Tip: Take with food
Astragalus is generally well-tolerated and considered safe for most healthy adults at recommended doses. The most commonly reported side effects are GI upset. Use caution if any of these apply to you: Autoimmune conditions (use with caution).
Curcumin
Likely helpsTurmeric's active compound that modulates NF-kB inflammatory pathways — supports mood, joint health, and post-exercise recovery.
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