Datta S et al. · J Nat Prod (2014)
Blue cohosh (Caulophyllum thalictroides) methanol extract exhibited mitochondriotoxic activity.
- Screened against 352 authenticated plant samples; blue cohosh was the one flagged as mitochondriotoxic
- The same mechanism has forced withdrawal or black-box warnings for major pharmaceuticals
- Notes the herb's use by some US midwives to induce labour