47 peer-reviewed studies · Evidence score: 8.5/10
Zhang Y et al. • Nutrients (2025)
However, further large-scale, well-designed randomized controlled trials (RCTs) are needed to confirm these findings, particularly those that include more standardized dosages and formulations, as well as to evaluate their long-term efficacy.
Dubey V et al. • Explore (New York, N.Y.) (2024)
BS supplementation is effective OA symptomatic management.
Del Grossi Moura M et al. • Phytotherapy research : PTR (2017)
Z. officinale showed improvement of pain over placebo.
Cameron M et al. • The Cochrane database of systematic reviews (2014)
Evidence for the proprietary ASU product Piasclidine® in the treatment of osteoarthritis symptoms seems moderate to high for short term use, but studies over a longer term and against an apparently active control are less convincing.
Kessler CS et al. • Rheumatology international (2015)
Well-planned, well-conducted and well-published trials are warranted to improve the evidence for Ayurvedic interventions.
Yu G et al. • BMC Complementary Medicine and Therapies (2020)
Boswellia significantly improved pain and function in knee OA.
Kafil TS et al. • The Cochrane database of systematic reviews (2017)
Low quality evidence suggests that budesonide may be effective for inducing and maintaining clinical and histological response in patients with collagenous colitis.
Wu YR et al. • Chinese journal of integrative medicine (2024)
The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature.
Bannuru RR et al. • Seminars in arthritis and rheumatism (2018)
The results of our study suggest that curcuminoid and boswellia formulations could be a valuable addition to the knee OA treatment regimens by relieving symptoms while reducing safety risks.
Dalmonte T et al. • Phytotherapy research : PTR (2024)
Phytotherapy Research
Efferth T et al. • Seminars in cancer biology (2022)
The therapeutic potential against other tumor types is still speculative.
Thomas RE et al. • International journal of environmental research and public health (2021)
Cleaning and disinfecting needs to include identifying biofilms on keyboards, tablets, cell phones, medical equipment (especially endoscopes), sinks, drains, and kitchens.
Salazar AS et al. • JNCI cancer spectrum (2021)
A limited number of chemoprevention agents have been shown to reduce MBD in premenopausal women.
Rossi RE et al. • European journal of gastroenterology & hepatology (2016)
In summary, attention to dietary factors such as curcumin, green tea and vitamins, including vitamins D and B12, appears to be beneficial and, if necessary, supplementation may be appropriate.
Langhorst J et al. • Journal of Crohn's & colitis (2015)
Complementary and alternative therapies might be effective for the treatment of inflammatory bowel diseases; however, given the low number of trials and the heterogeneous methodological quality of trials, further in-depth research is necessary.
Crawford C et al. • Pain medicine (Malden, Mass.) (2019)
Currently the scientific evidence is insufficiently robust to establish definitive clinical practice guidelines, but processes could be established to track the impact of these ingredients.
Liu X et al. • British journal of sports medicine (2018)
The overall analysis including all trials showed that supplements provided moderate and clinically meaningful treatment effects on pain and function in patients with hand, hip or knee osteoarthritis at short term, although the quality of evidence was very low.
De Silva V et al. • Rheumatology (Oxford, England) (2011)
The major limitation in reviewing the evidence is the paucity of randomized controlled trials in the area: widening the evidence base, particularly for those compounds for which there is promising evidence, should be a priority for both researchers and funders.
Inprasit C et al. • Complementary therapies in medicine (2026)
BS extract, particularly in modified formulations, improves joint function in patients with mild to moderate KOA, while only the modified formulation of CL demonstrates notable pain-reducing efficacy.
Chande N et al. • The American journal of gastroenterology (2009)
Budesonide is effective and well tolerated for inducing and maintaining clinical and histological responses in patients with collagenous colitis, and for inducing clinical and histological responses in patients with lymphocytic colitis.