1Meta-Analysis2015
Gauthier S, Proaño JV, Jia J, Froelich L, Vester JC, Doppler E · Dement Geriatr Cogn Disord (2015)
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84 peer-reviewed studies
What the evidence says
Most Cerebrolysin studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1990–2026 with a typical study size of 143 participants.
Based on 84 studies · 16 meta-analyses · 61 RCTs · 9,818 total participants
Confidence
High confidenceBy outcome
25 studies in the last 5 years · Latest meta-analysis: 2026
Gauthier S, Proaño JV, Jia J, Froelich L, Vester JC, Doppler E · Dement Geriatr Cogn Disord (2015)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Wang Z, Shi L, Xu S, Zhang J · Drug Des Devel Ther (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Wei ZH, He QB, Wang H, Su BH, Chen HZ · J Neural Transm (Vienna) (2007)
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Vester JC, Buzoianu AD, Florian SI, Hömberg V, Kim SH, Lee TMC · Neurol Sci (2021)
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El Sayed I, Zaki A, Fayed AM, Shehata GM, Abdelmonem S · Neurosurg Rev (2018)
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Zhang D, Dong Y, Li Y, Chen J, Wang J, Hou L · Biomed Res Int (2017)
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Fan F, Liu H, Shi X, Ai Y, Liu Q, Cheng Y · J Alzheimers Dis (2022)
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Bornstein NM, Guekht A, Vester J, Heiss WD, Gusev E, Hömberg V · Neurol Sci (2018)
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Cui S, Chen N, Yang M, Guo J, Zhou M, Zhu C · Cochrane Database Syst Rev (2019)
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Beghi E, Binder H, Birle C, Bornstein N, Diserens K, Groppa S · Eur J Neurol (2021)
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Eichel R, Teitcher M, Mausbach S, Poplavska A, Shqair S, Eichel R · J Stroke Cerebrovasc Dis (2026)
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Guekht A, Vester J, Heiss WD, Gusev E, Hoemberg V, Rahlfs VW · Neurol Sci (2017)
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Ziganshina LE, Abakumova T, Nurkhametova D, Ivanchenko K · Cochrane Database Syst Rev (2023)
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Flores-Sandoval C, Teasell R, MacKenzie HM, McIntyre A, Barua U, Mehta S · J Head Trauma Rehabil (2024)
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Finnegan E, Daly E, Pearce AJ, Ryan L · Front Nutr (2022)
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Gruenbaum SE, Zlotnik A, Gruenbaum BF, Hersey D, Bilotta F · CNS Drugs (2016)
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Guekht AB, Moessler H, Novak PH, Gusev EI, Ivanovna GS · J Stroke Cerebrovasc Dis (2011)
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Muresanu DF, Florian S, Hömberg V, Matula C, von Steinbüchel N, Vos PE · Neurol Sci (2020)
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Chang WH, Park CH, Kim DY, Shin YI, Ko MH, Lee A · BMC Neurol (2016)
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Woo PYM, Ho JWK, Ko NMW, Li RPT, Jian L, Chu ACH · BMC Neurol (2020)
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