1Meta-Analysis2023
Rastgoo S, Shimi G, Shiraseb F, Karbasi A, Ashtary-Larky D, Yousefi M · Front Immunol (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
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142 peer-reviewed studies
What the evidence says
CLA doesn't have enough studies with structured effect-size data yet to pool a verdict. Browse the studies below for individual findings.
Most evidence is from high-quality meta-analyses and randomised trials published 2000–2026.
Based on 142 studies · 21 meta-analyses · 115 RCTs
Confidence
High confidenceBy outcome
16 studies in the last 5 years · Latest meta-analysis: 2024
Rastgoo S, Shimi G, Shiraseb F, Karbasi A, Ashtary-Larky D, Yousefi M · Front Immunol (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Liang CW, Cheng HY, Lee YH, Liou TH, Liao CD, Huang SW · Nutr Rev (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Mirzaii S, Mansourian M, Derakhshandeh-Rishehri SM, Kelishadi R, Heidari-Beni M · Nutrition (2016)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Schoeller DA, Watras AC, Whigham LD · Appl Physiol Nutr Metab (2009)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Asbaghi O, Shimi G, Naseri K, Saadati S, Kelishadi MR, Doaei S · Eur J Pharmacol (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Morvaridzadeh M, Estêvão MD, Morvaridi M, Belančić A, Mohammadi S, Hassani M · Prostaglandins Other Lipid Mediat (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Namazi N, Irandoost P, Larijani B, Azadbakht L · Crit Rev Food Sci Nutr (2019)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Suksatan W, Putera HD, Abdulkadhim AH, Hammid AT, Ismailov JA, Jannat B · Clin Nutr ESPEN (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Haghighatdoost F, Nobakht M Gh BF · Eur J Clin Nutr (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Haghighat N, Shimi G, Shiraseb F, Karbasi A, Nadery M, Ashtary-Larky D · Pharmacol Res (2022)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Ghodoosi N, Rasaei N, Goudarzi K, Hashemzadeh M, Dolatshahi S, Omran HS · Nutr J (2023)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Derakhshande-Rishehri SM, Mansourian M, Kelishadi R, Heidari-Beni M · Public Health Nutr (2015)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Mazidi M, Karimi E, Rezaie P, Ferns GA · Cardiovasc Ther (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Onakpoya IJ, Posadzki PP, Watson LK, Davies LA, Ernst E · Eur J Nutr (2012)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Whigham LD, Watras AC, Schoeller DA · Am J Clin Nutr (2007)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Rahbar AR, Ostovar A, Derakhshandeh-Rishehri SM, Janani L, Rahbar A · Endocr Metab Immune Disord Drug Targets (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Yang J, Wang HP, Zhou LM, Zhou L, Chen T, Qin LQ · Lipids Health Dis (2015)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Haghighatdoost F, Hariri M · Endocr Metab Immune Disord Drug Targets (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Mohammadi-Sartang M, Sohrabi Z, Esmaeilinezhad Z, Aqaeinezhad R SM, Jalilpiran Y · Horm Metab Res (2018)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: This review critically examines CLA's molecular role in obesity and metabolic regulation, providing insights into its therapeutic promise and limitations.
Rajendran M, Palani S, Singh TG, Oliver B, Dua K, Subramaniyan V, Narayanan K. · Food science & nutrition (2025)