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Clm5.5
Colostrum Research
Likely helps
172 peer-reviewed studies
What the evidence says
Likely helps
Colostrum appears to help in 3 of 3 studies with measurable effects — the evidence leans clearly favourable.
Most evidence is from high-quality meta-analyses and randomised trials published 1982–2026 with a typical study size of 116 participants.
Based on 172 studies · 18 meta-analyses · 119 RCTs · 7,494 total participants
Confidence
High confidence
What the studies found
3helped· 169 more without graded effect data
By outcome
Women's health
Mostly mechanism / observational30 studies
Neonatal & pediatric clinical
Mostly mechanism / observational29 studies
Immune support & infectionsEnhanced mucosal immunity · 2-4 weeks
Mostly mechanism / observational28 studies
Gastrointestinal & gut barrierImmunoglobulins support gut barrier integrity and repair · 2-4 weeks
19Athletic performance in soccer playersMeta-AnalysisCited 6×2025
This study suggests that a range of dietary supplements, including caffeine, creatine, creatine + sodium bicarbonate, magnesium creatine chelate, carbohydrate + electrolyte, carbohydrate + protein, arginine, beta-alanine, bovine colostrum, Kaempferia parviflora, melatonin, and sodium pyruvate, can improve athletic performance in soccer players.
Luo H et al. · Journal of the International Society of Sports Nutrition (2025)
Kaempferia parviflora (SMD: 0.46, small) was associated with a significant effect on enhancing muscular strength.
Beta-alanine (SMD: 0.83, moderate), melatonin (SMD: 0.75, moderate), caffeine (SMD: 0.37, small), and creatine (SMD: 0.33, small) were associated with a significant effect on enhancing jump height.
Magnesium creatine chelate (SMD: -3.0, very large), melatonin (SMD: -1.9, large), creatine + sodium bicarbonate (SMD: -1.4, large), and arginine (SMD: -1.2, moderate) were associated with a significant effect on decreasing sprint time.
The present systematic review and meta-analysis provides evidence that bovine colostrum supplementation may be effective in preventing the incidence of URS days and episodes in adults engaged in exercise training.
Jones AW et al. · BMC Sports Science, Medicine and Rehabilitation (2016)
Over an 8-12 week follow-up period, bovine colostrum supplementation when compared to placebo significantly reduced the incidence rate of URS days (rate ratio 0.56, 95 % confidence intervals 0.43 to 0.72, P value < 0.001) and URS episodes (0.62, 0.40 to 0.99, P value = 0.04) by 44 and 38 % respectively.
Five trials (152 participants) met the inclusion criteria, all of which involved individuals involved in regular exercise training.
The present systematic review and meta-analysis provides evidence that bovine colostrum supplementation may be effective in preventing the incidence of URS days and episodes in adults engaged in exercise training.