65 peer-reviewed studies · Evidence score: 9/10
Arabi SM et al. • Phytotherapy research : PTR (2026)
This meta-analysis demonstrates that curcumin supplementation improves liver function, albumin levels, SOFA scores, and ICU stay duration in critically ill patients, suggesting its potential role in mitigating organ dysfunction in this population.© 2026 John Wiley & Sons Ltd.
Zhang Y et al. • Nutrients (2025)
However, further large-scale, well-designed randomized controlled trials (RCTs) are needed to confirm these findings, particularly those that include more standardized dosages and formulations, as well as to evaluate their long-term efficacy.
Cheng YC et al. • Psychological medicine (2025)
This extensive systematic review and NMA of nutraceuticals for treating depressive disorders indicated a number of nutraceuticals that could offer benefits, either as adjuncts or monotherapies.
Jafari A et al. • Phytotherapy research : PTR (2024)
Trial registration: PROSPERO: CRD42021251969.
Yu L et al. • The journal of prevention of Alzheimer's disease (2025)
Preclinical in vivo evidence suggests curcumin enhances cognitive function in AD models.
Fusar-Poli L et al. • Critical Reviews in Food Science and Nutrition (2024)
Curcumin supplementation shows anxiolytic effects in clinical populations.
Qiu L et al. • Frontiers in endocrinology (2023)
Curcumin exhibited promising potential in enhancing markers associated with metabolic syndrome, including inflammation.
Zeng L et al. • Frontiers in immunology (2022)
Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis.
Yang K et al. • Frontiers in immunology (2022)
Based on current evidence, curcumin can reduce BMI, TG, TC, liver enzymes, and insulin resistance; catechin can reduce BMI, insulin resistance, and TG effectively; silymarin can reduce liver enzymes.
Sahebkar A et al. • Pharmacological Research (2016)
Curcumin supplementation significantly reduces CRP levels, a key marker of systemic inflammation.
Mathieu S et al. • Nutrients (2022)
Other studies are needed to better assess the effects of omega-3 and vitamin D.
Guo Y et al. • Phytotherapy research : PTR (2025)
Phytotherapy Research
Moradi Baniasadi M et al. • Nutrition & diabetes (2025)
This meta-analysis examined the effects of Curcumin.
Shen W et al. • Frontiers in endocrinology (2022)
In light of presented findings, curcumin has beneficial effects on serum markers of inflammation, weight loss and glucose and lipid metabolism in patients with PCOS.
Mokgalaboni K et al. • Nutrients (2024)
While the potential benefits were observed, it is recommended that future trials focus on finding a suitable dose and duration of intervention and incorporate formulation in curcumin to enhance its absorption.
Dehzad MJ et al. • Cytokine (2023)
It seems that turmeric/curcumin supplementation might be used as a viable intervention for improving inflammatory/oxidative status of individuals.
Kou H et al. • Frontiers in immunology (2023)
Curcumin is beneficial for rheumatoid arthritis treatment.
Doyle L et al. • Alternative therapies in health and medicine (2023)
Turmeric extract and curcumin supplements can be effective adjuvants for the management of musculoskeletal health, with a low incidence of AEs.
Zeng L et al. • Frontiers in immunology (2022)
Curcumin and Curcuma longa Extract had good clinical efficacy in the treatment of Psoriasis, UC and RA, so Curcumin and Curcuma longa Extract could be used in the treatment of the above diseases in the future.
Ng QX et al. • Journal of the American Medical Directors Association (2017)
Curcumin appears to be safe, well-tolerated, and efficacious for depression.