Eleutherococcus senticosus (Siberian Ginseng)
Adaptogen that supports endurance, stress resilience, and immune function — distinct from true ginseng.
Eleuthero, formerly called Siberian Ginseng, is a hardy adaptogen used extensively in Russia for performance, stress, and immune support. Unlike Panax ginseng, it doesn't contain ginsenosides but has its own active compounds (eleutherosides). Research supports benefits for endurance, fatigue reduction, and immune function. Gentler and less stimulating than Panax ginseng.
Modulates stress response and improves resilience
Supports healthy immune function
How Eleuthero works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
300-1200mg extract (standardized to 0.8% eleutherosides)
Take with food
| Form | Type |
|---|---|
| 💊Standardized root extract | Recommended |
| 💊Dried root | Alternative |
| 💧Tincture | Alternative |
Look for standardization to eleutherosides. Root is the traditional part used.
Minimum: 4 weeks
Optimal: 12 weeks
Cycling: 6-8 weeks on, 2 weeks off. Russian practice was continuous for months.
Note: Take earlier in the day. Can be mildly stimulating.
Less mental and physical fatigue
Improved physical endurance
Insufficient data; avoid
May interfere with digoxin assays
Theoretical interaction
Tip: Take earlier in day; reduce dose
Top studies from 22+ peer-reviewed papers
Lopresti AL et al. • Nutritional neuroscience (2022)
“For most phytonutrients, the effects of supplementation on HPA-axis activity in humans is unclear.”
Kos G et al. • Molecules (Basel, Switzerland) (2025)
“Still, its conservation and sustainable production are critical and require ongoing research and innovative cultivation strategies.”
Flagg AJ • The Nursing clinics of North America (2021)
“Three major types of ginseng are described.”
Li T et al. • The American journal of Chinese medicine (2016)
“This paper reviews recent findings on the pharmacological properties of A. senticosus, with a focus on its anticancer effects.”
Alkhatib A et al. • Journal of the International Society of Sports Nutrition (2015)
“The multi-ingredient product's potential enhancement of FAO during exercise, satiety, and RPE reduction suggests an acute effectiveness of SHRED in improving the exercise-related fat loss benefits.”
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