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Elt3.5
Eleuthero – Forschung
Überwiegend Mechanismus / Beobachtung
26 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Eleuthero sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1986–2022 mit einer typischen Studiengröße von 92 Teilnehmenden.
Basierend auf 26 Studien · 1 Meta-Analyse · 16 RCTs · 485 Teilnehmende insgesamt
Konfidenz
Mittlere Konfidenz
Was die Studien gefunden haben
1geholfen· 25 weitere ohne bewertete Effektdaten
Nach Outcome
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung5 Studien
Endurance & exercise performanceEine systematische Übersichtsarbeit strenger Studien fand keinen Vorteil für die Ausdauer · 4-8 weeks
Überwiegend Mechanismus / Beobachtung4 Studien
Energy & fatigueTraditionell bei Müdigkeit und für Energie verwendet, doch kontrollierte Studien konnten keinen Nutzen nachweisen · 2-8 weeks
Überwiegend Mechanismus / Beobachtung3 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung3 Studien
Women's health
Überwiegend Mechanismus / Beobachtung3 Studien
Cognitive function
Zu wenige bewertete Studien2 Studien
Anxiety & stressTraditionelles Adaptogen gegen Stress, doch die Wirkung auf die HPA-Achse beim Menschen bleibt in Studien unklar · 2-4 weeks · Adaptogene Stress-Behauptungen sind in kontrollierten Humanstudien nicht belegt · 4-8 weeks
Zu wenige bewertete Studien1 Studie
Immune supportImmunmodulatorische Aktivität in vitro beobachtet; klinischer Nutzen beim Menschen nicht belegt · 4-8 weeks
Zu wenige bewertete Studien1 Studie
Safety profile
Zu wenige bewertete Studien1 Studie
In Zahlen
Aus 8 Studien mit messbaren Effekten gezogen
Untersuchte Personen
485
typische Studie: 92 Personen
Stärkste Designs
17
1 gepoolt, 16 randomisiert
Zeigte Nutzen
100%
1/1 Studien
Untersuchte Populationen
Humans1
Cancer patients1
General population1
Hypertensive patients1
Lässt nach
Nur 2 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2009
198620042022
1Übersicht2021
Einfach gesagt: The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection.
Todorova V et al. · Nutrients (2021)
Extracts from Panax ginseng, Eleutherococcus senticosus, Rhaponticum carthamoides, Rhodiola rosea, and Schisandra chinensis are considered to be naturally occurring adaptogens and, in particular, plant adaptogens.
About 50 years ago, plant adaptogens were first used in professional sports due to their high potential to increase the body's resistance to stress and to improve physical endurance.
Although now many people take plant adaptogens, the clinical trials on human are limited.
Einfach gesagt: This paper reviews recent findings on the pharmacological properties of A. senticosus, with a focus on its anticancer effects.
Li T et al. · The American journal of Chinese medicine (2016)
In the past decades, researchers worldwide have conducted systematic investigations on this herb, from chemistry to pharmacology, and a large number of chemical components have been characterized for their significant pharmacological effects.
However, reports about the anticancer effects of this plant had been rare until recently, when considerable pharmacological experiments both in vitro and in vivo were conducted to study the anticancer effects of this herb.
A. senticosus has been found to have inhibitory effects on malignant tumors, such as those in the lung and liver, suggesting that A. senticosus has potential to be developed as an effective anticancer drug.
5Pharmacological activities of Acanthopanax senticosusÜbersicht2011
Einfach gesagt: The present review is an up-to-date and comprehensive analysis of the botany, chemistry, pharmacology, toxicity and clinical trials of AS.
Huang L et al. · Die Pharmazie (2011)
In recent decades, a great number of chemical, pharmacological, and clinical studies on AS have been carried out worldwide.
Several kinds of chemical compounds have been reported, including triterpenoid saponins, lignans, coumarins, and flavones, among which, phenolic compounds such as syringin and eleutheroside E, were considered to be the most active components.
Considerable pharmacological experiments both in vitro and in vivo have persuasively demonstrated that AS possessed anti-stress, antiulcer, anti-irradiation, anticancer, anti-inflammatory and hepatoprotective activities, etc.
6Blood pressure effects of dietary supplementsÜbersicht2012
Einfach gesagt: The goals and objectives of this review are to discuss the regulation of DS, evaluate the efficacy of particular DS in the treatment of hypertension, and highlight DS that may potentially increase blood pressure.
Rasmussen CB et al. · Journal of clinical hypertension (Greenwich, Conn.) (2012)
Patients with hypertension often choose to use these products either in addition to or instead of pharmacologic antihypertensive agents.
Because of the frequent use of DS, both consumers and health care providers should be aware of the considerable issues surrounding these products and factors influencing both efficacy and safety.
The goals and objectives of this review are to discuss the regulation of DS, evaluate the efficacy of particular DS in the treatment of hypertension, and highlight DS that may potentially increase blood pressure.
7Complementary medicine efficacy for genital herpesÜbersicht2005
Einfach gesagt: It is hoped that future clinical trials will be conducted with sufficient rigour to provide guidance to the patients using these products.
Perfect MM et al. · Herpes : the journal of the IHMF (2005)
We have reviewed available scientific data on six commonly used treatments (echinacea, eleuthero, L-lysine, zinc, bee products and aloe).
In addition, information about a number of other products is presented in tabular form.
Currently, there are insufficient clinical data to be confident of the efficacy and safety of any of these products for the treatment of genital herpes.
8Systematische Übersicht2005
Einfach gesagt: It is therefore concluded that ES supplementation (up to 1000 to 1200 mg/d for 1 to 6 wk) offers no advantage during exercise ranging in duration from 6 to 120 min.
Goulet ED et al. · International journal of sport nutrition and exercise metabolism (2005)
This article reviews the studies that evaluated the effects of ES during endurance exercise, three of which suggest that ES substantially improves CF, FAM, and EP.
However, each of these reports contains severe methodological flaws, which seriously threaten their internal validity, thereby rendering hazardous the generalization of the results.
On the other hand, 5 studies that used rigorous research protocols show no benefit of ES on CF, FAM, and EP.