He T, Yang W, Zhang X, Li P, Yang D, Wu Y · Medicine (Baltimore) (2020)
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140 peer-reviewed studies
What the evidence says
Most Exemestane studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1997–2026 with a typical study size of 20 participants.
Based on 140 studies · 14 meta-analyses · 117 RCTs · 1,290 total participants
Confidence
High confidenceBy outcome
18 studies in the last 5 years · Latest meta-analysis: 2025
He T, Yang W, Zhang X, Li P, Yang D, Wu Y · Medicine (Baltimore) (2020)
Yu Z, Guo X, Jiang Y, Teng L, Luo J, Wang P · Breast Cancer (2018)
Sun R, Chu Y, Gao Y, Cheng W, Gao S · Menopause (2021)
He Y, Zhang J, Shen G, Liu L, Zhao Q, Lu X · BMC Pharmacol Toxicol (2019)
Hadji P, Asmar L, van Nes JG, Menschik T, Hasenburg A, Kuck J · J Cancer Res Clin Oncol (2011)
Xu L, Zhang Z, Xiang Q, Liu Q, Duan X, Liu Y · Clin Breast Cancer (2019)
Robertson JFR, Paridaens RJ, Lichfield J, Bradbury I, Campbell C · Eur J Cancer (2021)
Bradley R · Lancet Oncol (2022)
Zhang J, Huang Y, Wang C, He Y, Zheng S, Wu K · Medicine (Baltimore) (2017)
Wang W, Liu C, Zhou W, Xia T, Xie H, Wang S · Sci Rep (2016)
Mocellin S, Goodwin A, Pasquali S · Cochrane Database Syst Rev (2019)
Gibson L, Lawrence D, Dawson C, Bliss J · Cochrane Database Syst Rev (2009)
Nelson HD, Fu R, Zakher B, Pappas M, McDonagh M · JAMA (2019)
Hind D, Ward S, De Nigris E, Simpson E, Carroll C, Wyld L · Health Technol Assess (2007)
Eisen A, Trudeau M, Shelley W, Messersmith H, Pritchard KI · Cancer Treat Rev (2008)
Liao H, Pei W, Zhong J, Shao B, Liu X, Liu Y · Front Pharmacol (2022)
Riemsma R, Forbes CA, Kessels A, Lykopoulos K, Amonkar MM, Rea DW · Breast Cancer Res Treat (2010)
Beresford M, Tumur I, Chakrabarti J, Barden J, Rao N, Makris A · Clin Oncol (R Coll Radiol) (2011)
Coleman RE, Banks LM, Girgis SI, Vrdoljak E, Fox J, Cawthorn SJ · Breast Cancer Res Treat (2010)
Groenewoud G, Nell A, Potgieter L, Seiler D, Wettmarshausen C · Arzneimittelforschung (2010)