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4 peer-reviewed studies
What the evidence says
Most Garcinia Cambogia studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from medium-quality randomised trials published 1998–2018 with a typical study size of 135 participants.
Based on 4 studies · 1 RCT · 135 total participants
Confidence
LowBy outcome
Newest study from 2018
A landmark randomized trial (n=135) found Garcinia cambogia (hydroxycitric acid) FAILED to produce weight or fat loss beyond placebo.
Heymsfield SB et al. · JAMA (1998)
A literature review of Garcinia/HCA for weight loss found inconsistent results and no established effective dosage.
Fassina P et al. · Nutr Hosp (2015)
A review of Garcinia cambogia for weight loss concluded the evidence is weak and flagged hepatotoxicity reports.
Haber SL et al. · Am J Health Syst Pharm (2018)
A trial evaluated the safety and efficacy of hydroxycitric acid.
Marquez F et al. · Crit Rev Food Sci Nutr (2012)