Ginkgo biloba Extract
Improves cerebral blood flow and peripheral circulation — modest evidence for memory in older adults and cognitive decline.
Ginkgo biloba extract comes from the leaves of the ancient ginkgo tree. It's commonly used for cognitive enhancement and circulation. Research shows modest benefits for memory in older adults and those with cognitive decline, but effects in healthy young adults are less consistent. Also used for peripheral circulation issues.
Enhances circulation to the brain and extremities
Protects brain cells from oxidative damage
May modulate neurotransmitter systems
How Ginkgo Biloba works — from molecular targets to health outcomes. Click an edge to see supporting research.This visualization is in beta — pathways are being refined and expanded.
120-240mg standardized extract
Take with food
| Form | Type |
|---|---|
| 💊Standardized extract capsules (EGb 761) | Recommended |
| 💊Tablets | Alternative |
| 💧Liquid extract | Alternative |
EGb 761 is the most studied standardized extract. Avoid raw ginkgo leaves which contain toxic compounds.
Minimum: 6 weeks
Optimal: 12 weeks
Cycling: Not required
Note: Use standardized extract containing 24% flavone glycosides and 6% terpene lactones. Effects build over weeks.
Better recall, especially in older adults
Improved blood flow to extremities
Some experience headaches initially
Avoid due to bleeding risk and insufficient data
Avoid or use only under medical supervision
Increases bleeding risk
May reduce seizure threshold
Possible increased bleeding risk
Tip: Start with lower dose
Tip: Take with food
Tip: Reduce dose
Traditional combination for cognitive support
May enhance cognitive benefits more than either alone
Different mechanisms for memory support
Comprehensive cognitive enhancement
Both enhance cerebral circulation
Enhanced brain blood flow and cognition
Top studies from 39+ peer-reviewed papers
Xie L et al. • Cells (2022)
“Nevertheless, the preclinical and clinical data suggest that further large-scale clinical trials may be needed in order to examine the effects of long-term GEB administration on early-stage AD.”
Mousavi SN et al. • Phytotherapy research : PTR (2022)
“Therefore, this medicinal herb might be a possible strategy for inflammation control.”
Soares-Weiser K et al. • The Cochrane database of systematic reviews (2018)
“This review has found that the use of valbenazine or extract of Ginkgo biloba may be effective in relieving the symptoms of tardive dyskinesia.”
Whitton ME et al. • The Cochrane database of systematic reviews (2015)
“This review has found some evidence from individual studies to support existing therapies for vitiligo, but the usefulness of the findings is limited by the different designs and outcome measurements and lack of quality of life measures.”
Riepe M et al. • The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2025)
“The meta-analysis demonstrates that patients with mild dementia benefit from EGb 761 in terms of cognition, activities of daily living, global assessment and quality of life.”
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