1Meta-Analysis2020
Zhao J, Huang W, Zhang S, Xu J, Xue W, He B · Am J Rhinol Allergy (2020)
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91 peer-reviewed studies
What the evidence says
Most Glutathione studies are mechanism or observational rather than RCTs that measure a clinical effect — keep findings provisional.
Most evidence is from high-quality meta-analyses and randomised trials published 1983–2026 with a typical study size of 1,019 participants.
Based on 91 studies · 3 meta-analyses · 78 RCTs · 1,213 total participants
Confidence
High confidenceBy outcome
8 more outcomes with fewer studies not shown.
22 studies in the last 5 years · Latest meta-analysis: 2026
Zhao J, Huang W, Zhang S, Xu J, Xue W, He B · Am J Rhinol Allergy (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology.
Etani T et al. · Neuropsychopharmacology reports (2026)
Nasiri MJ, Khoshdel N, Venketaraman V · Int J Tuberc Lung Dis (2025)
No plain-language summary recorded for this citation — open the paper to read its abstract.
In plain English: Such supplementation can be beneficial, and it is most effective when combined with a diet rich in sulfur-containing foods and other nutrients that support GSH synthesis.
Bradauskienė V et al. · Nutrients (2026)
Dilokthornsakul W, Dhippayom T, Dilokthornsakul P · J Cosmet Dermatol (2019)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Nabipur L, Mouawad M, Venketaraman V · Viruses (2025)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Arosio E, De Marchi S, Zannoni M, Prior M, Lechi A · Mayo Clin Proc (2002)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Kern JK, Geier DA, Adams JB, Garver CR, Audhya T, Geier MR · Med Sci Monit (2011)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Puckett TR, Peele KA, Howard RS, Kramer KK · Ophthalmology (1995)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Bozic M, Goss CH, Tirouvanziam RM, Baines A, Kloster M, Antoine L · J Pediatr Gastroenterol Nutr (2020)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Amano J, Suzuki A, Sunamori M · J Am Coll Surg (1994)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Leone R, Fracasso ME, Soresi E, Cimino G, Tedeschi M, Castoldi D · Cancer Chemother Pharmacol (1992)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Lenzi A, Culasso F, Gandini L, Lombardo F, Dondero F · Hum Reprod (1993)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Arrivi A, Pucci G, Dominici M, Mangieri E, Tanzilli G · J Cardiovasc Med (Hagerstown) (2021)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Stoldt G, Struck HG · Ophthalmologe (1997)
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Corti A, Griese M, Hector A, Pompella A · J Cyst Fibros (2017)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Nayak BK, Jain EK · Indian J Ophthalmol (2009)
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Griese M, Ramakers J, Krasselt A, Starosta V, Van Koningsbruggen S, Fischer R · Am J Respir Crit Care Med (2004)
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He SX, Qiao W, Chang XM, Wang SY, Li HX · Zhonghua Gan Zang Bing Za Zhi (2004)
No plain-language summary recorded for this citation — open the paper to read its abstract.
Rosenfeld SI, Waltman SR, Olk RJ, Gordon M · Ophthalmology (1986)
No plain-language summary recorded for this citation — open the paper to read its abstract.