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Studien
Gl5.8
Glycerol – Forschung
Überwiegend Mechanismus / Beobachtung
76 begutachtete Studien
Was die Evidenz sagt
Überwiegend Mechanismus / Beobachtung
Die meisten Studien zu Glycerol sind mechanistisch oder beobachtend statt RCTs, die einen klinischen Effekt messen — betrachte die Ergebnisse als vorläufig.
Die meiste Evidenz stammt aus hochwertigen Meta-Analysen und randomisierten Studien, veröffentlicht 1972–2026 mit einer typischen Studiengröße von 403 Teilnehmenden.
Basierend auf 76 Studien · 10 Meta-Analysen · 60 RCTs · 1,117 Teilnehmende insgesamt
Konfidenz
Hohe Konfidenz
Was die Studien gefunden haben
2geholfen· 74 weitere ohne bewertete Effektdaten
Nach Outcome
Endurance & exercise performanceVerlängerte Zeit bis zur Erschöpfung, besonders bei Hitze · 1-2 Stunden (akute Anwendung) · Hyperhydratation; verbessert die Ausdauer bei Hitze · 60-120 Minuten
Überwiegend Mechanismus / Beobachtung23 Studien
Therapeutic & clinical
Überwiegend Mechanismus / Beobachtung15 Studien
Heart & blood pressure
Überwiegend Mechanismus / Beobachtung6 Studien
RecoveryBesserer Hydratationsstatus für die Regeneration · Sofort
Zu wenige bewertete Studien2 Studien
Safety profile
Zu wenige bewertete Studien2 Studien
In Zahlen
Aus 5 Studien mit messbaren Effekten gezogen
Wahrscheinlich echte Effekte
50%
über Studien hinweg
Untersuchte Personen
1,117
typische Studie: 403 Personen
Stärkste Designs
70
10 gepoolt, 60 randomisiert
Zeigte Nutzen
100%
2/2 Studien
Untersuchte Populationen
Athletes1
Combat sports athletes1
Healthy individuals1
Cyclists in esports and gravel disciplines1
Stetige Forschung
16 Studien in den letzten 5 Jahren · Neueste Meta-Analyse: 2024
197219992026
1Meta-Analyse2007
Goulet ED, Aubertin-Leheudre M, Plante GE, Dionne IJ · Int J Sport Nutr Exerc Metab (2007)
Einfach gesagt: While no moderating effects were observed, lack of heterogeneity makes it difficult to generalise these findings.
McCubbin Aj et al. · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme (2024)
Spürbar Nutzen
← SchlechterKein EffektBesser →
Likely real
Meta-analysis determined overall effect size (Hedges' g), and meta-regression the influence of independent moderators (ambient temperature, hyperhydration agent, exercise mode, extent of hyperhydration).
A small-to-moderate improvement in time-to-exhaustion (TTE) (Hedges' g = 0.31, 95% CI: 0.13-0.50, p = 0.001) and time trial (TT) (g = 0.25, 95% CI: 0.002-0.51, p = 0.049) but not total work (TW) tasks (p = 0.120) was found following hyperhydration.
No effects were found for perceived exertion or thermal comfort.
Einfach gesagt: Caffeine is the only NEA that has shown strong evidence for performance enhancement in combat sports.
Vicente-Salar N et al. · Nutrients (2022)
In this regard, abilities including the number of attacks, reaction time, handgrip strength, power and TTE, among others, were improved.
Buffering supplements such as sodium bicarbonate, sodium citrate and beta-alanine may have a promising role in high and intermittent exertion during combat, but more studies are needed in grappling combat sports to confirm their efficacy during sustained isometric exertion.
Other NEAs, including creatine, beetroot juice or glycerol, need further investigation to strengthen the evidence for performance enhancement in combat sports.
Einfach gesagt: In comparison with other plasma-volume expanding agents, glycerol hyperhydration has a very limited potential in increasing plasma volume and altering doping-relevant blood parameters.
Koehler K et al. · Drug testing and analysis (2013)
Kaum spürbar Nutzen
← SchlechterKein EffektBesser →
The meta-analysis revealed that the increase in plasma volume was 3.3% larger (95%-CI: 1.1-5.5%) after glycerol administration when compared to fluid only.
Reductions in haemoglobin were 0.2 g/dl (95%-CI: -0.3, 0.0) larger and there was no difference in the changes in haematocrit between glycerol and fluid administration (95%-CI: -0.7-0.8%).
Following a literature search, a total of seven studies was included and meta-analyses were performed separately for the effects on plasma volume (5 studies, total n = 54) and on haemoglobin (6 studies, n = 52) and haematocrit (6 studies, n = 52).
Einfach gesagt: While performance supplements may enhance athletic performance when used alongside proper nutrition and scientific guidance, their effectiveness is not always consistent or assured.
Estevan Navarro P et al. · Nutrients (2025)
While performance supplements may enhance athletic performance when used alongside proper nutrition and scientific guidance, their effectiveness is not always consistent or assured.
This review highlights the urgent need to update regulatory frameworks, harmonize labeling standards, and promote ethical marketing to safeguard consumers and support sports and nutrition professionals.
Einfach gesagt: However, no statistically significant effects were identified for the remaining supplements, whether administered individually or in combination.
Valiño-Marques A et al. · Nutrients (2024)
However, no statistically significant effects were identified for the remaining supplements, whether administered individually or in combination.
Thirty-six articles involving 701 participants were included in this review, examining supplementation with caffeine (n = 5), creatine (n = 2), sodium bicarbonate (n = 6), beta-alanine (n = 3), and nitrates (n = 8).
Additionally, supplemental combinations of caffeine and creatine (n = 3), caffeine and sodium bicarbonate (n = 3), caffeine and nitrates (n = 1), creatine and sodium bicarbonate (n = 1), and sodium bicarbonate and beta-alanine (n = 4) were analyzed.